DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and R09B5.11

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_503413.2	Gene:	R09B5.11 / 178634	WormBaseID:	WBGene00019979	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	500	Identity:	140/500 - (28%)
Similarity:	233/500 - (46%)	Gaps:	73/500 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SVPADGLKANFTFSQVLAALSVSLCSLVVGF-VSAYTSPALVSMTDRTITSFEVTKDAGS----- 72
            |:|.:    |:|........|::|.|...|| :....:|..:.:.......||:..:..|
Worm    37 SLPDE----NWTPFLFFCISSIALASFQDGFQIGCINAPGPLIIDWIKKCHFELFGEVLSQYQAD 97

  Fly    73 --W--------VGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACA--VNVI-M 124
              |        |||:.      |....|.|.:..||:||:|...:..:::::.::.:  .|.. |
Worm    98 FIWSVAVSMFSVGGMF------GSFCSGFLADKFGRKSTLLYNNILALLAAVCLSTSKLFNFYPM 156

  Fly   125 ILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLG-----------LLPTALGNIGILVCYVAG 178
            |:.||||.|...||.|..:|::|.|.....:||..|           :|..|||     :..:.|
Worm   157 IVFGRFLVGLNCGITSGLVPMFLTELAPANLRGKCGSFHQLNISVAIVLSQALG-----LPQIFG 216

  Fly   179 SFMNWSMLAFLGAALPVPFLILMIIIP---ETPRWFVNR-GQEERARKALKWLRGKEADVEPELK 239
            :.:.|   .::.|.:.:|..:.:..||   |:|::.::: ...|.||:.|:.||| ...|:.||:
Worm   217 TQVGW---PYIFACVAIPTFLQLATIPFCVESPKYLISKLNDREEARRILEKLRG-HTKVDEELE 277

  Fly   240 ELMQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAG-STID 303
            .::|..........|...:.|||.:|..|:.:|:.:||.||||||:||.||:..|||..| |..:
Worm   278 HMVQETMVTVEPLHQPGYVSLFKGDNQWPMIVSILMMFSQQFSGISAVTFYSTLIFKRNGLSGNE 342

  Fly   304 SNLSTIIVGVVNFFATFMGIILID--RLGRKIL-------LYVSDIAMIVTLSILGGFFYCKAHG 359
            ...:|:..|.:...|||..:.|||  :.|||.|       :.:|.|.:::||::....::.
Worm   343 PMYATVGFGCIKLIATFGCLFLIDHPKFGRKRLHIAGLSGMCISSILIVITLTLSNAGYHW---- 403

  Fly   360 PDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQ 424
              .|::..|.:..||:   .|:.|.|||||....|:..:..||.||:|....||...::|..||.
Worm   404 --ASYMNVLFILSFVV---TFAFGPGPIPWFFTSELFDSATRGRAAAVSATSNWVANWMVGLTFL 463

  Fly   425 DLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKM 469
            .:...:..: ||.:|.........|...|||||:|||...|.:::
Worm   464 PINNIIHQY-AFLMFTFFTFTFAIFTWKFVPETKGKSPSAIRKEL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	136/479 (28%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	127/464 (27%)
R09B5.11	NP_503413.2	Sugar_tr	54..499	CDD:278511	132/469 (28%)
R09B5.11	NP_503413.2	MFS	90..465	CDD:119392	115/398 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810