DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tret1-2 and Slc2a9

DIOPT Version :9

Sequence 1:NP_610694.1 Gene:Tret1-2 / 36249 FlyBaseID:FBgn0033644 Length:488 Species:Drosophila melanogaster
Sequence 2:NP_001095884.1 Gene:Slc2a9 / 117591 MGIID:2152844 Length:538 Species:Mus musculus


Alignment Length:502 Identity:135/502 - (26%)
Similarity:220/502 - (43%) Gaps:89/502 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 FTFSQVLAAL------------SVSLCSLVVGFVSAYTS-------------PALVSMTDRTITS 63
            ::||.|:|||            ::|:.:....::.|:.:             ..|..:...|::.
Mouse    33 WSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGTWYRRHGQPIDPDTLTLLWSVTVSI 97

  Fly    64 FEVTKDAGSWVGGIMPLAALAGGITGGPLI----EYLGRRSTILATAVPFIVSSLLIACAVNV-- 122
            |.:                  ||:.|..::    ::|||:||:|......|.::||:||::..  
Mouse    98 FAI------------------GGLVGTLMVKMIGKFLGRKSTLLVNNGFAISAALLMACSLRAGT 144

  Fly   123 -IMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSML 186
             .|::.|||:.|...|||..:||:||.|....|:||:||.: ||     |.:|....|.....:.
Mouse   145 FEMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQV-TA-----IFICIGVFSGQLLGLP 203

  Fly   187 AFLGAALPVPFLILMIII------------PETPRWFV-NRGQEERARKALKWLRGKEADVEPEL 238
            ..||.....|:|..:||:            ||:||:.: .:..|..|.||.:...|| |||..||
Mouse   204 ELLGRESTWPYLFGVIIVPALVQLASLPFLPESPRYLLFEKHDEAGAMKAFQTFLGK-ADVSQEL 267

  Fly   239 KELMQSQADADRQATQNTCLELFKRNNLKPLSISLGL-MFFQQFSGINAVIFYTVQIFKDAGSTI 302
            :|.: :::...|.....:.|||.:...::...|::.: |...|..|:||:.|||..||..||...
Mouse   268 EEAL-AESRVQRNLRLVSVLELLRAPFVRWQVITVIITMASYQLCGLNAIWFYTNSIFGKAGIPQ 331

  Fly   303 DS----NLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKAHGPDVS 363
            |.    .|||  .|:....|.|.|:: |:||||:.||......|.:....|......:...|   
Mouse   332 DKIPYITLST--GGIETLAAIFSGLV-IERLGRRPLLIGGFGLMALFFGTLTATLTLQDQAP--- 390

  Fly   364 HLGWLP---LTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQD 425
               |:|   :.|.:..|..|..|.|.||:::.||......|..|..:....||...|.|...|..
Mouse   391 ---WVPYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGLLFPF 452

  Fly   426 LTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGR 472
            :..::.:: .|.:|..|||.|..:....:|||:.::..||.:....|
Mouse   453 IQKSLDSY-CFLVFATICIAGATYFYFVLPETKNRTHAEISQAFAKR 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tret1-2NP_610694.1 Sugar_tr 31..467 CDD:278511 131/488 (27%)
MFS 33..454 CDD:119392 124/473 (26%)
Slc2a9NP_001095884.1 MFS_GLUT_Class2 40..491 CDD:340990 129/486 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 495..538 1/4 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167834417
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X26
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.840

Return to query results.
Submit another query.