Protein Alignment Tret1-2 and SLC2A13

DIOPT Version :9

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_443117.3
• Gene: SLC2A13 / 114134
• HGNCID: 15956
• Length: 648
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 143/548 - (26%)
• Similarity: 221/548 - (40%)
• Gaps: 128/548 - (23%)

  Fly    26 FSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDA-------GSWVGGIMPLAAL 83
            |..|:|..| :|...:.|:.:...|.|::      :...:::.||       .|.||     ||.
Human    80 FVYVVAVFS-ALGGFLFGYDTGVVSGAML------LLKRQLSLDALWQELLVSSTVG-----AAA 132

  Fly    84 AGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLG 148
            ...:.||.|....|||:.||..:..|...|.::|.|.|...:|.||.:.|..:||||:::|||:.
Human   133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIA 197

  Fly   149 ETLQPEVRGTLGLLPTALGNIG-ILVCYVAGSFM-----NWSMLAFLGAALPVPFLILMIIIPET 207
            |...|.:||.|..:.|.....| .....|.|:|.     .|..:..|.|...|......:.:||:
Human   198 EVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPES 262

  Fly   208 PRWFVNRGQEERARKALKWLRGKEA----------DVEPELKELMQSQADADRQATQNTCLELFK 262
            |||.:.:||.::||:.|..:||.:.          ::|.|.||:        ..|....|..|..
Human   263 PRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEV--------GSAGPVICRMLSY 319

  Fly   263 RNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGV---VNFFATFMGII 324
            ....:.|.:..||..|||.||||.:::|:..|.:.:| ..|..|:..:..|   .||..|.:|:.
Human   320 PPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSG-VEDDRLAIWLASVTAFTNFIFTLVGVW 383

  Fly   325 LIDRLGRKILLYVSDIAMIVTLSILG-GFF---------------------------YC------ 355
            |::::||:.|.:.|.....|.|.||. ||.                           ||
Human   384 LVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLD 448

  Fly   356 ---------------------------------------KAHGPDV--------SHLGWLPLTCF 373
                                                   |....|:        :...|..|...
Human   449 PDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGL 513

  Fly   374 VIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWL 438
            ::|::.|:.|.||:||.:..||.|...|....:..:..||....:|:.||......:..:|||:|
Human   514 ILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFL 578

  Fly   439 FGAICIVGLFFVIIFVPETRGKSLEEIE 466
            :.....|||.|:...:|||:||.|||||
Human   579 YAGFAAVGLLFIYGCLPETKGKKLEEIE 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	141/543 (26%)
		MFS	33..454	CDD:119392	130/527 (25%)
SLC2A13	NP_443117.3	Sugar_tr	84..609	CDD:278511	141/544 (26%)
		MFS	86..591	CDD:119392	130/525 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144082
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750