DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and slc2a9

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_002936818.2	Gene:	slc2a9 / 100495427	XenbaseID:	XB-GENE-5883703	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	133/507 - (26%)
Similarity:	226/507 - (44%)	Gaps:	92/507 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DGLKANFTFSQVLAALSVSLCSLVVGFVSAYTSP-------ALVSMTDRTITSFEVTKDAGSW-- 73
            |..|..|...||...|:.||  |.|..:|::.|.       |:|:.....|.:|..|    :|
Frog     2 DKKKRVFAAKQVTGNLTFSL--LAVSLLSSFGSSMLYGYNLAVVNSPSEYIKAFYNT----TWNQ 60

  Fly    74 -----------------VGGIMPLAALAGGITGGPLIEYLGRRSTIL-ATAVPFIVSSLLIACAV 120
                             ...:..|..:.|.:..|.|:...||:.||: :|.:.|:...|:....:
Frog    61 RYGEALEQSPLTLMYSLTVSVFALGGMLGSLLVGILVSRFGRKGTIIRSTPLVFVAGGLMGLSRI 125

  Fly   121 --NVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYV------A 177
              :..|::.|||:||...||:...:|:||||.....:||.|||:|:....:|:....|      .
Frog   126 FSSPEMVIIGRFITGIHSGISLSVVPMYLGEISPKNLRGLLGLVPSIFICLGVFSAQVLGLPELL 190

  Fly   178 GSFMNWSMLAFLGAALPVPFLILMIII---PETPRW-FVNRGQEERARKALKWLRGKEADVEPEL 238
            |....|.:  ||...: ||..:.::::   ||:||: .:::........||:...| |.||:..:
Frog   191 GQDETWPL--FLSLVV-VPTFVQLVLLPWFPESPRYLLIDKSNVHGTIDALRCFLG-EYDVQDVI 251

  Fly   239 KELMQSQADADRQATQNTCL-----ELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDA 298
            :|:.:.|.......|.:.|.     .||.: .|..:.|::|:    |.|||:|:.|||..||::|
Frog   252 EEMQEEQKSFSSVDTVSVCQFLSDPTLFWQ-ILSVIVINIGM----QLSGIDAIWFYTNSIFENA 311

  Fly   299 GSTI-DSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGF----FYC--- 355
            |..: :...:|:..|.:...|..:|...:::|||:.||             :|||    |.|
Frog   312 GIPMAEIPYTTVGTGAIEIVAGLIGCFTVEKLGRRPLL-------------IGGFSFMGFCCAGI 363

  Fly   356 ------KAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVV-TAFNW 413
                  :|..|.:.::.   :.|.:..|.||.:|...:|:::.||:.....| |||.:| ...||
Frog   364 TLALVFQARVPVMRYVS---VACVIGIIAGFCIGPAGLPFIITGELFTQSHR-PAAFIVGGTLNW 424

  Fly   414 FCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEI 465
            ...|.|...|..|.::.||. .:.:|..||:....:|...:|||:.::..||
Frog   425 LSNFTVGFVFPFLQISAGAF-CYMVFCGICLFVAAYVYYIIPETKNRTFMEI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	128/494 (26%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	123/479 (26%)
slc2a9	XP_002936818.2	MFS_GLUT_Class2	30..475	CDD:340990	120/475 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910