DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_038967504.1	Gene:	Slc2a7 / 100362644	RGDID:	1583902	Length:	525	Species:	Rattus norvegicus

Alignment Length:	499	Identity:	151/499 - (30%)
Similarity:	249/499 - (49%)	Gaps:	66/499 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VPADGLKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITS------FEVTKD---- 69
            :|:..::|....:.||..||.:..|   .|...| :.|:::...:..||      |:|.|.
  Rat    10 LPSPHMEARLQPTLVLTTLSAAFGS---AFQYGY-NIAVINTPHKVGTSSGWGPVFQVLKSFYND 70

  Fly    70 -----AGSWVG------------GIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIA 117
                 .|:::.            .:.||..|.|.:..|.::...||:.|:|...|..|.|::|:.
  Rat    71 TYFERHGTFMDENTLLLLWSCTVSMFPLGGLLGSLVVGMMVNKWGRKRTLLINNVFAITSAVLMG 135

  Fly   118 ---CAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCY---- 175
               .|....:|:..|.:.|.|.|||..:||:||||.....:|||||.:.......|:|:..
  Rat   136 ASKAARAFELIIFSRVMVGICAGIAYSTLPMYLGELAPQNLRGTLGTMTEVFVIFGVLLAQIFSL 200

  Fly   176 --VAGSFMNWS-MLAFLGAALPVPFLILMI---IIPETPRW-FVNRGQEERARKALKWLRGKEAD 233
              :.|:...|. :||..|    ||.||.::   ..||:||: .:.:|.||..|:||:.|||...:
  Rat   201 QTILGNATGWPILLALTG----VPALIQLLSLPFFPESPRYTLIEKGDEETTRQALRRLRGHSYN 261

  Fly   234 VEPELKELMQSQADADRQATQNTCLELFKRNNLKPLSISL-GLMFFQQFSGINAVIFYTVQIFKD 297
            ||.|::| |:::...::...:.:.|.||....|:...||: .||..||.||||||.:|...|:..
  Rat   262 VEAEMEE-MRTEERTEKAEGRLSVLNLFTFRPLRWQLISIVVLMAGQQLSGINAVNYYADIIYTS 325

  Fly   298 AG-STIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILL-----YVSDIAMIVTLSILGGFFYCK 356
            || ....|...|:..||:|...|.:...:|:||||:|||     ......:::|:::|     .:
  Rat   326 AGVDPTQSQYVTLGSGVINLVMTLVSAFIIERLGRRILLLSGYGICGSACLVLTVALL-----LQ 385

  Fly   357 AHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTK 421
            :..|::|:||   :.|...||:|.|:|..|:|.::..||:....|..|.:|..|.:|...|:|..
  Rat   386 STVPELSYLG---IICVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGAVHWLTNFIVGL 447

  Fly   422 TFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEI 465
            ||..:.||:||: :|.:|..||::...::.:.:|||:||:..||
  Rat   448 TFPSIQVAIGAY-SFLIFAGICLLTAAYIYVVIPETKGKTFVEI 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	147/483 (30%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	140/468 (30%)
Slc2a7	XP_038967504.1	MFS_GLUT_Class2	26..490	CDD:340990	145/481 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337726
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840