DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and slc2a7

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001120033.1	Gene:	slc2a7 / 100144999	XenbaseID:	XB-GENE-5811422	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	493	Identity:	126/493 - (25%)
Similarity:	213/493 - (43%)	Gaps:	78/493 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LAALSVSLCSLVVGFVSAY-TSPALVSMTDRTITSF---------EVTKDAG------SWVGGIM 78
            ::.|.:::|::.:|....| .:.::::...|.|..|         :...:.|      |.:..:.
Frog    17 ISRLFLAVCAVGIGGAFQYGYNVSIINAPTRQIQQFINNTWYSRHQSNLEEGWLTLIWSVIASVF 81

  Fly    79 PLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN---VIMILCGRFLTGFCVGIAS 140
            .|..|.|...||.|.:.|||:.|:|...|..|:::.|:..|..   ..:::.||.:.|...||..
Frog    82 TLGGLLGTHIGGHLADKLGRKKTLLMNNVLAILAAFLMGIAYPSGCFELLIVGRLIIGINAGIGL 146

  Fly   141 LSLPVYLGETLQPEVRG--TLGLLPTALGNI------GILVCYVAGSFMNWSMLAFLGAALP--- 194
            ...|:||||.....:||  |:|:.....|.|      |:...:..|.  ||..|      ||
Frog   147 CVQPLYLGEIAPRHIRGLTTVGMNIFLTGGIFTGQLVGLRELFGGGD--NWYFL------LPTCC 203

  Fly   195 VPFLILMIII---PETPRWFVNRGQEE-RARKALKWLRGKEADVEPELKELMQSQADADRQATQN 255
            :|.:|.:..:   ||:||:.:...::| :.:||||.|.|.| ..:||:.::::.....:.:..:
Frog   204 IPAIIQLASLPWFPESPRYLLIENKDEYQCQKALKMLYGSE-HYQPEMDDILKESCALNGEKPK- 266

  Fly   256 TCLELFKRNNLK-PLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSN---LSTIIVGVVNF 316
            |..:||....:: .|.|.:.....||.|||||:.||...:|..||  |.:|   ..|:..|:...
Frog   267 TIFQLFSDRTVRWQLVIIILTNIGQQLSGINAIYFYAAYVFTKAG--IPANNIPYVTLGTGLCEC 329

  Fly   317 FATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGF----FYC-----KAHGPDVSHLGWLP--- 369
            .......:|||..||:||             |:||:    |:|     .....||  ..|:|
Frog   330 LTALTCGLLIDIAGRRIL-------------IIGGYTLMAFWCTILTLTLTFQDV--YPWIPYLS 379

  Fly   370 LTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHG 434
            ::....:||.|.||.|.:...:..|:.....|..|..:..:..|...|.:...|..|...:..:
Frog   380 MSAVFAFILSFGLGPGGVTNTLTAELFTQSSRSAAFRISGSVGWITFFTIGMIFPFLVNGLNQY- 443

  Fly   435 AFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGR 472
            .|..|...|::...|:...||||:.||..||:::...|
Frog   444 CFLFFFVECLLTASFIFFIVPETKNKSFLEIKKEFQKR 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	125/485 (26%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	117/470 (25%)
slc2a7	NP_001120033.1	MFS_GLUT_Class2	23..474	CDD:340990	122/478 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910