Protein Alignment Tret1-1 and ATR2

DIOPT Version :9

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_014006.1
• Gene: ATR2 / 855322
• SGDID: S000004892
• Length: 540
• Species: Saccharomyces cerevisiae
• Alignment Length: 673
• Identity: 124/673 - (18%)
• Similarity: 210/673 - (31%)
• Gaps: 254/673 - (37%)

  Fly   275 FKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSI 339
            ||....:||:.::.||        ::..:.||         |.:.|..||:..|
Yeast     5 FKKKTSVQGTDSEIDE--------KITVKAKD---------KVVVSTEDEEVTT----------- 41

  Fly   340 STDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIY----------IW 394
            ...|.||                        .|:|.|.        |..:|.|          |.
Yeast    42 IVSSTKS------------------------TQVTNDS--------PWQDPTYFSSFGKELMFIA 74

  Fly   395 TQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSFEVTQDAG--SWVGGIMPLAGLAGGIAG 457
            |.:||.|....|.          :.||..|   |:.|.....:|.  :|:....|||..:..:..
Yeast    75 TCMLAQLLNQAGQ----------THALCIM---NVLSKSFNSEANNQAWLMASFPLAAGSFILIS 126

  Fly   458 GPLIEYLGRRNTILATAVPFIVSSLLIACAV---NVAMVLCGRFLAGFCVGIASLSLPVYLGETV 519
            |.|.:..|.:..::...|..||.|::...:.   :.|..:..|...|  ||||.
Yeast   127 GRLGDIYGLKKMLIVGYVIVIVWSIISGLSKYSNSDAFFITSRAFQG--VGIAF----------- 178

  Fly   520 QPEVRGTLGLLPTAFGNIGILLCFVAGSFMNWSMLAFLGAALPVPFLILMF-------LIPETP- 576
                     :||...|.:|.:  :..|||....:::|:||..|...   ||       ::.|.|
Yeast   179 ---------ILPNIMGLVGHV--YKVGSFRKNIVISFIGACAPTGG---MFGGLFGGLIVTEDPN 229

  Fly   577 RW---FVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKLNNL---- 634
            :|   |...|:.......:.|. ....:|...:.||     ..|...|...::.|:..|.:
Yeast   230 QWPWVFYAFGIATFLSLLMAWY-SIPNNVPTNIHGL-----SMDWTGSALAIIGLILFNFVWNQA 288

  Fly   635 ------KPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVL 693
                  ||..|.|.::         :|||                    :|....:.:.:..:.|
Yeast   289 PIVGWDKPYIIVLLII---------SVIF--------------------LVAFFVYESKYAEVPL 324

  Fly   694 IDRA---GRKILLYVSDIAMVLTLFVLGGFFY------CKTYGP--------------------- 728
            :.||   .|.:::.:..:.:....|.:..|:|      .:.|.|
Yeast   325 LPRAMTKNRHMIMILLAVFLGWGSFGIWTFYYVSFQLNLRHYSPVWTGGTYFVFVIFGSMAAFFV 389

  Fly   729 --DVSHLGWLPLTCF-----------------------------VIYILGFSLGFGPIPWLMMGE 762
              .:..||...|.||                             .|...|..|.| |...:::.:
Yeast   390 AFSIKRLGPALLLCFSLMAFDAGSIMFSVLPVEQSYWKLNFAMQAILCFGMDLSF-PASSIILSD 453

  Fly   763 ILPAKIRGSAAS-VATAFNWFCTFV----------VTKTFQDLTVAMGAHGAFWLFGAICFVGLF 816
            .||.:.:|.|.| |.|..|:..:..          :.|:..||  ..|...|.:|...:..:|:.
Yeast   454 GLPMQYQGMAGSLVNTVINYSASLCLGMGGTVEHQINKSGNDL--LKGYRAAVYLGVGLASLGVV 516

  Fly   817 FVIIYVPE--------TQGKTLE 831
            ..:.|:.|        ::.::||
Yeast   517 ISVTYMLENLWNRHRKSEDRSLE 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	105/566 (19%)
		MFS	401..822	CDD:119392	94/518 (18%)
ATR2	NP_014006.1	MFS_Amf1_MDR_like	74..519	CDD:341029	97/522 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900