Protein Alignment Tret1-1 and ITR2

DIOPT Version :9

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 596
• Identity: 140/596 - (23%)
• Similarity: 252/596 - (42%)
• Gaps: 106/596 - (17%)

  Fly   284 SSTD-SDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSR 347
            :||| |..:||:..|::......|..||                        ::..:||.:.:.:
Yeast    32 ASTDQSSTQGEELHHRKHCEEDNDGQKP------------------------KKSPVSTSTMQIK 72

  Fly   348 RLYEMDEMDNKRGENIRHAVPFVRQIT-EDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVG 411
            ...:.||.|.:         ..::.:. ||....:..:..:.:|..|....:|::|    ..:.|
Yeast    73 SRQDEDEDDGR---------IVIKPVNDEDDTSVIITFNQSISPFIITLTFVASIS----GFMFG 124

  Fly   412 FVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVP 476
            :.:.|.|.||:|: :|::.:..:|......:.....|..|...:..|...:..|||..::.:.:.
Yeast   125 YDTGYISSALISI-NRDLDNKVLTYGEKELITAATSLGALITSVGAGTAADVFGRRPCLMFSNLM 188

  Fly   477 FIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILL 541
            |::.::|...|.....:..||.:.||.|||.||..|:::.|.....:||.|.::.:.:...|.|:
Yeast   189 FLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLI 253

  Fly   542 CFVAGSFMN-----WSMLAFLGAALPVPFLILMF----LIPETPRWFVGRGLEERARKALKWLRG 597
            .:..|:.:|     |.:|  :|.:| :| .:|.|    .:|:|||::|.:|..:||:..||
Yeast   254 AYGCGAGLNHVKNGWRIL--VGLSL-IP-TVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLK---- 310

  Fly   598 KEADVEPELKGLMRSQADADRQASRNTMLELLKLN------------------------NLKPLS 638
                         ||..:.:.:.....:.||..||                        |.:.|.
Yeast   311 -------------RSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALI 362

  Fly   639 ISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILL 703
            |..||...|||:|.|::::::..||:..|.. :.:..:|||...||:.|.|....||:.||:.:|
Yeast   363 IGCGLQAIQQFTGWNSLMYFSGTIFETVGFK-NSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYIL 426

  Fly   704 YVSDIAMVLTLFVLGGFFY---CKTYGPDV-------SHLGWLPLTCFVIYILGFSLGFGPIPWL 758
            .:....|.:.|.:....|:   .|..|.|.       |..|.:.:...::|...::||.|.:||
Yeast   427 LIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAFYALGIGTVPW- 490

  Fly   759 MMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVP 823
            ...|:.|..:||...|.|||.||..:.|:..||..:...:...|.|..|..:..:...|.....|
Yeast   491 QQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFCYP 555

  Fly   824 ETQGKTLEDIE 834
            |..|..||:::
Yeast   556 ELSGLELEEVQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	123/493 (25%)
		MFS	401..822	CDD:119392	115/463 (25%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	116/468 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342408
Domainoid	1	1.000	166	1.000	Domainoid score	I806
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2166
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.770