Protein Alignment Tret1-1 and VPS73

DIOPT Version :10

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 485
• Identity: 113/485 - (23%)
• Similarity: 199/485 - (41%)
• Gaps: 89/485 - (18%)

  Fly   399 AALSVSLGSLVVGF-VSAYTSPALVSMTDRNITSFEVTQDA----GSWVG--------------- 443
            |.:..|:||:..|: :|...:|..|    .:.:.|::..:.    .:|:|
Yeast    31 AIIVASIGSIQFGYHLSELNAPQQV----LSCSEFDIPMEGYPYDRTWLGKRGYKQCIPLNDEQI 91

  Fly   444 GIMPLAGLAGGIAGG----PLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCV 504
            ||:......|||.|.    .|....||:.:.|......||.||:|..:.:...::.||.|.|...
Yeast    92 GIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIGRILVGISC 156

  Fly   505 GIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCF-----VAGSFMNWSMLAFLGAALPVP 564
            |...:.:|:::.|.......|.||.:......:|:||..     :..|: .|..:.|....:.|.
Yeast   157 GSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSY-RWRWILFGSFLIAVL 220

  Fly   565 FLILMFLIPETPRWFVGRGLEERARKALKWLRGKEAD-------------------VEPELKGLM 610
            ...:.|::.|:|:|.:..|....|:.:|..|||...|                   :||
Yeast   221 NFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPLIEP------ 279

  Fly   611 RSQADADRQASRNTMLELLK-LNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNL 674
               ...:..:..|::.:.|: ..|:|...:...|:|.|||.|||:::.|        |:.|...|
Yeast   280 ---TTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLY--------GTKIISQL 333

  Fly   675 -------CTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTYGPDVSH 732
                   ....:.:||.|.|.:..:||....||.||..|.:.:.:|.|::|       ...:.:.
Yeast   334 YPQHAIRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMG-------IAMNHNK 391

  Fly   733 LGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVA 797
            :..|.:..| ||:..|::|..|:|:::|.|:...:....|....|..||..||::..||..:...
Yeast   392 MNLLIVFSF-IYMGVFTMGLNPLPFIIMREVSKPQDMVLAQRYGTICNWVGTFIIAYTFPIIHDV 455

  Fly   798 MGAHGAFWLFGAI-CFVGLFFVIIYVPETQ 826
            :..: .|.:|..| |.:.. |:...||||:
Yeast   456 LSGY-VFIIFAIIACSISA-FIWKKVPETK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	MFS_GLUT6_8_Class3_like	397..832	CDD:340916	113/485 (23%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	113/485 (23%)