DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tret1-1 and STP1

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_172592.1	Gene:	STP1 / 837667	AraportID:	AT1G11260	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	147/524 - (28%)
Similarity:	233/524 - (44%)	Gaps:	93/524 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 ITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGF---VSA------------------- 415
            :..||:   :.|.....|..::|.|:||    :|.|:.|:   :|.
plant     7 VVGDGQ---KAYPGKLTPFVLFTCVVAA----MGGLIFGYDIGISGGVTSMPSFLKRFFPSVYRK 64

  Fly   416 ------------YTSPALVSMTDRNITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRN 468
                        |.||.|...|..                  :.||.|...:....:....|||.
plant    65 QQEDASTNQYCQYDSPTLTMFTSS------------------LYLAALISSLVASTVTRKFGRRL 111

  Fly   469 TILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTA 533
            ::|...:.|...:|:...|.:|.|::.||.|.||.:|.|:.::|:||.|....:.||.|.:....
plant   112 SMLFGGILFCAGALINGFAKHVWMLIVGRILLGFGIGFANQAVPLYLSEMAPYKYRGALNIGFQL 176

  Fly   534 FGNIGILLCFVAGSFM-----NWSMLAFLGAALPVPFLIL---MFLIPETPRWFVGRGLEERARK 590
            ...||||:..|...|.     .|.....||.|: ||.||:   ..::|:||...:.||..|.|:.
plant   177 SITIGILVAEVLNYFFAKIKGGWGWRLSLGGAV-VPALIITIGSLVLPDTPNSMIERGQHEEAKT 240

  Fly   591 ALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKLNNLKPLSISLGLMFFQQFSGINAV 655
            .|:.:||.: ||..|...|:  .|..:.|:..:....||:......|::::.:.||||.:|||.:
plant   241 KLRRIRGVD-DVSQEFDDLV--AASKESQSIEHPWRNLLRRKYRPHLTMAVMIPFFQQLTGINVI 302

  Fly   656 IFYTVQIFKDAGSTIDGNLCT-IIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGG 719
            :||...:|...|.|.|.:|.: ::.|.||..||.:.|..:||.||:.|.......|::...|:..
plant   303 MFYAPVLFNTIGFTTDASLMSAVVTGSVNVAATLVSIYGVDRWGRRFLFLEGGTQMLICQAVVAA 367

  Fly   720 FFYCKTYGPDVSHLGWLP-------LTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVAT 777
            ....| :|.|.:. |.||       :|...||:.||:..:||:.||:..||.|.:||.:|.|:..
plant   368 CIGAK-FGVDGTP-GELPKWYAIVVVTFICIYVAGFAWSWGPLGWLVPSEIFPLEIRSAAQSITV 430

  Fly   778 AFNWFCTFVVTKTFQDLTVAMGAH---GAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMG 839
            :.|...||::.:.|    :.|..|   |.|.:|.....|...||.|::|||:|..:|:     ||
plant   431 SVNMIFTFIIAQIF----LTMLCHLKFGLFLVFAFFVVVMSIFVYIFLPETKGIPIEE-----MG 486

  Fly   840 RVRR 843
            :|.|
plant   487 QVWR 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	141/503 (28%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	130/473 (27%)
STP1	NP_172592.1	MFS_STP	29..476	CDD:340919	132/478 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.720