DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and ESL1

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_849618.1	Gene:	ESL1 / 837413	AraportID:	AT1G08920	Length:	477	Species:	Arabidopsis thaliana

Alignment Length:	464	Identity:	134/464 - (28%)
Similarity:	233/464 - (50%)	Gaps:	30/464 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 NPIYIWTQVLAALSVSL-GSLVVGFVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPLAGLA 452
            |...|...||.:..||: ||...|..:.|:|.|...:.  |.....|.|  .|..|.||...|:.
plant    24 NECRITAVVLFSTFVSVCGSFCFGCAAGYSSVAQTGII--NDLGLSVAQ--YSMFGSIMTFGGMI 84

  Fly   453 GGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGE 517
            |.|..|.:.:.:||:.|:....:..|...:.:|.|.:...:..||...||.||:.|..:|||:.|
plant    85 GAIFSGKVADLMGRKGTMWFAQIFCIFGWVAVALAKDSMWLDIGRLSTGFAVGLLSYVIPVYIAE 149

  Fly   518 TVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMNWSMLAFLG---AALPVPFLILMFLIPETPRWF 579
            .....|||..........:.|:.|.:|.|:|::|..||.:|   .||.|   :.:|.|||:||..
plant   150 ITPKHVRGAFVFANQLMQSCGLSLFYVIGNFVHWRNLALIGLIPCALQV---VTLFFIPESPRLL 211

  Fly   580 VGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKLNNLKPLSISLGLM 644
            ...|.|:..|.:|:.|||.:||:..|...:..:....| :..::.:::|.:......:.|.:|||
plant   212 GKWGHEKECRASLQSLRGDDADISEEANTIKETMILFD-EGPKSRVMDLFQRRYAPSVVIGVGLM 275

  Fly   645 FFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIA 709
            ..||.||.:.:::|...:|...|  ...::.::|:.::......:|::|:::.||:.||.::|:.
plant   276 LLQQLSGSSGLMYYVGSVFDKGG--FPSSIGSMILAVIMIPKALLGLILVEKMGRRPLLLMNDLY 338

  Fly   710 M------VLTLFVLGGFFYC-KTYG--PDVSHLGWLPLTCF--VIYILGFSLGFGPIPWLMMGEI 763
            :      :....:|..|.:| ::||  .:::.:    .||.  |.:|..|::|.|.:||::|.||
plant   339 LQASTGGMCFFSLLLSFSFCFRSYGMLDELTPI----FTCIGVVGFISSFAVGMGGLPWIIMSEI 399

  Fly   764 LPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGK 828
            .|..::.||.::.|..||...::|...: :..:...|.|.|.:|..||..|:.|:...||||:|:
plant   400 FPMNVKVSAGTLVTLANWSFGWIVAFAY-NFMLEWNASGTFLIFFTICGAGIVFIYAMVPETKGR 463

  Fly   829 TLEDIERKM 837
            |||||:..:
plant   464 TLEDIQASL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	132/458 (29%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	120/435 (28%)
ESL1	NP_849618.1	Sugar_tr	36..469	CDD:278511	129/447 (29%)
ESL1	NP_849618.1	MFS	36..457	CDD:119392	120/435 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I356
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930