DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and VGT1

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_186959.2	Gene:	VGT1 / 821117	AraportID:	AT3G03090	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	147/497 - (29%)
Similarity:	246/497 - (49%)	Gaps:	49/497 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 ITEDGKPKLEVYRPTTNPIYIWTQVLAA----LSVSLGSLVVGFVSAYTSPALVSM---TDRNIT 430
            ||.:.:|.|:......|     ..||||    |..:||:|:.|:....||.|::|:   |...|:
plant    25 ITAEKEPLLKENHSPEN-----YSVLAAIPPFLFPALGALLFGYEIGATSCAIMSLKSPTLSGIS 84

  Fly   431 SFEVTQ-DAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVL 494
            .::::. |.|....|.: ...|.|.|....:.:.:|||..::..|..::|.:::...|...::::
plant    85 WYDLSSVDVGIITSGSL-YGALIGSIVAFSVADIIGRRKELILAAFLYLVGAIVTVVAPVFSILI 148

  Fly   495 CGRFLAGFCVGIASLSLPVYLGETVQPEVRG---TLGLLPTAFGNIG------ILLCFVAGSFMN 550
            .||...|..:|:...:.|:|:.||...::||   :|....|..|.:|      :.:..::|
plant   149 IGRVTYGMGIGLTMHAAPMYIAETAPSQIRGRMISLKEFSTVLGMVGGYGIGSLWITVISG---- 209

  Fly   551 WSMLAFLGAALPVPFLI--LMFLIPETPRWFV---------GRGLEERARKALKWLRGKE-ADVE 603
            |..:  ....||.|.::  .|..:|.:|||.:         |..|::.|.::|..|||.. ||..
plant   210 WRYM--YATILPFPVIMGTGMCWLPASPRWLLLRALQGQGNGENLQQAAIRSLCRLRGSVIADSA 272

  Fly   604 PELKGLMRSQADADRQASRNTMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAG- 667
            .|....:.::.....:....|..||.:...||.|:|:.||:.|||.:|..:|::|...|.:.||
plant   273 AEQVNEILAELSLVGEDKEATFGELFRGKCLKALTIAGGLVLFQQITGQPSVLYYAPSILQTAGF 337

  Fly   668 -STIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTYGPDVS 731
             :..|....:|::|::..:.|.:.:::|||.||:.||......||::||:||.::......|.|:
plant   338 SAAADATRISILLGLLKLVMTGVSVIVIDRVGRRPLLLCGVSGMVISLFLLGSYYMFYKNVPAVA 402

  Fly   732 HLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTV 796
                  :...::|:..:.|.||||.|||:.||.|.|:||...|:|...|:....:||..|..|..
plant   403 ------VAALLLYVGCYQLSFGPIGWLMISEIFPLKLRGRGISLAVLVNFGANALVTFAFSPLKE 461

  Fly   797 AMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMM 838
            .:||...|..||.||.|.|||:...||||:|.|||:||.|.:
plant   462 LLGAGILFCAFGVICVVSLFFIYYIVPETKGLTLEEIEAKCL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	140/481 (29%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	127/447 (28%)
VGT1	NP_186959.2	MFS_GLUT10_12_Class3_like	53..498	CDD:340920	134/457 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780