Protein Alignment Tret1-1 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 140/484 - (28%)
• Similarity: 242/484 - (50%)
• Gaps: 44/484 - (9%)

  Fly   401 LSVSLGSLVVGF---------VSAYTSPALVSMTDRNITSF----EVTQD-----AGSWVGGIMP 447
            |.::|.:|:..|         |:|..||||:.....|.|.:    |..:|     ..|....:.|
Human    15 LVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMFP 79

  Fly   448 LAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIAC---AVNVAMVLCGRFLAGFCVGIASL 509
            ..|..|.:..|||:...||:..:|...:..||.::|:.|   |.:..:::..|.|.|.|.|::|.
Human    80 FGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSN 144

  Fly   510 SLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAG------SFMNWS-MLAFLGAALPVPFLI 567
            .:|:||||.....:||.||::|..|..:|||:..:.|      :...|. :|...|....:..|:
Human   145 VVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLL 209

  Fly   568 LMFLIPETPRW-FVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKL 631
            |.| .||:||: .:.:..|..|:|||:.|||.:: |:.|:..: |.:.:|::.|...::|:|.::
Human   210 LPF-FPESPRYLLIQKKDEAAAKKALQTLRGWDS-VDREVAEI-RQEDEAEKAAGFISVLKLFRM 271

  Fly   632 NNLK--PLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDG-NLCTIIVGIVNFLATFIGIVL 693
            .:|:  .||| :.||..||.||:||:.:|..||:..||...:. ...|...|.||.:.||..:.:
Human   272 RSLRWQLLSI-IVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFV 335

  Fly   694 IDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWL 758
            ::..||::||.:.....::...||......:   ..||.:.::.:.|.:.|::|.:||..|||.|
Human   336 VELLGRRLLLLLGFSICLIACCVLTAALALQ---DTVSWMPYISIVCVISYVIGHALGPSPIPAL 397

  Fly   759 MMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVP 823
            ::.||.....|.||..|..:.:|...|.|...|..:...:|.: :|.:|..||.:...::.:.||
Human   398 LITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPY-SFIVFAVICLLTTIYIFLIVP 461

  Fly   824 ETQGKTLEDIERKMMGRVRRMSSVANIKP 852
            ||:.||..:|.:..    .:|:.|:.:.|
Human   462 ETKAKTFIEINQIF----TKMNKVSEVYP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	MFS_GLUT6_8_Class3_like	397..832	CDD:340916	136/462 (29%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	133/455 (29%)