DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and CG14160

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_648380.2	Gene:	CG14160 / 39177	FlyBaseID:	FBgn0036066	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	113/549 - (20%)
Similarity:	199/549 - (36%)	Gaps:	162/549 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 VPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFV--------SAYTSPALVS 423
            :|.:..|.|:.  ||...|      .:|...|...|::..|:|  ||        |.:.:||...
  Fly     1 MPMLPTIEEEA--KLSWIR------LMWKYRLQFQSMASASIV--FVGCGMRLAWSIFDTPAGKF 55

  Fly   424 MTDRNITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGR-RNTILATAVPFIVSSLLIACA 487
            :.:.|..:..::...|:.||.:  ||.|           ::.| ...:..|:..|:   ::||..
  Fly    56 LNNHNTHNLMMSWFIGAAVGAL--LAAL-----------FVQRVTKNVAYTSSGFL---MIIAGI 104

  Fly   488 VNVAMVLCGRFLA--------GFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILL--- 541
            :||  ||...|||        |...|:..:...|...|.....:||.|......|..:|:.:
  Fly   105 LNV--VLPQHFLAACYSSVSVGAAYGLTQIQALVTGSEVAHKSIRGMLLSCEKIFLWLGVCMQVF 167

  Fly   542 -------------------------CFVAGSFMNWSMLAFLGAALPVPFLILM----FLIPETPR 577
                                     ..:||..:...:|| |...|..|.|:|.    ..:.||.:
  Fly   168 YTRVWHNLRPLDTQGYEMHIDQLHGMVLAGLGLGAVILA-LAHRLESPLLLLHQERDMAVGETLK 231

  Fly   578 WFVGRGLEERAR---------KALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKLNN 633
            ...|:...|..|         .|..|.|..|   |||       ::.||.:.....:|...|:..
  Fly   232 ALHGQSTTELVRLREDCRQLHSARDWERFVE---EPE-------ESVADWRVWARRILPFFKVLL 286

  Fly   634 LK---PLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLID 695
            |:   .|::||      .::....|:.:       .|...|.| |...:.....:.:.:|..::|
  Fly   287 LRCFATLAVSL------SYNRAFVVVSW-------HGLECDMN-CMYWLAFAGLIGSVLGAFVVD 337

  Fly   696 RAGRK----ILLYVSDIAMVLTLFVLGGFFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIP 756
            ..||:    :.|:::.:.:|:    :||.|         .||..:..:.:.|.:|..:|
  Fly   338 WQGRRKVCSLSLFLAGVVIVM----VGGVF---------DHLESVKRSFYDINLLVIAL------ 383

  Fly   757 WLMM--------GEILPAKI-RGSAASVATAFNWFCTFVVTK----------TFQD-LTVAMGAH 801
             ||:        |..:||.: ...|.|:|.........::.:          ||:. :||::
  Fly   384 -LMLLFEVIVAGGVAVPALVYTAEAFSIAHKARCLAGILIVEQLLQLGLLLATFEHYITVSV--- 444

  Fly   802 GAFWLFGAICFVGLFFVIIYVPETQGKTL 830
             .|:..|...|:....|.:::|||:..||
  Fly   445 -FFFTIGVFSFIVGLTVFMFMPETRQLTL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	108/534 (20%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	100/505 (20%)
CG14160	NP_648380.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740