DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and CG4797

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	161/558 - (28%)
Similarity:	255/558 - (45%)	Gaps:	64/558 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 ESDEDFLTSRQH-----------FQQQRSISTDSRKSRRLYEMDEMD----NKRGENIRHAVPFV 370
            |.|:::|....|           ||.:::    |..||:|..:||.|    |:||  :.|
  Fly     4 ERDDEYLKFVPHTMSYQVVPGSEFQCKKA----SYSSRKLSTIDEQDDDAANRRG--MMH----- 57

  Fly   371 RQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSFEVT 435
                                     |:||..:|.|.|...|....:::..|..:.|.|.|...:.
  Fly    58 -------------------------QILATCAVLLLSAGCGMPIGFSAILLPQLMDNNSTEIPID 97

  Fly   436 QDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLA 500
            .:.|||:..:..||...|.:..|||.:|||||.|::.:.:|.::....:|.|.::.:|:..|||.
  Fly    98 VETGSWIASVHSLATPFGSLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLC 162

  Fly   501 GFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMNWSMLAFLGAALPVPF 565
            ||..||......||:.||.:|.:|..|...|....:.|||:.:..||.|.|..:|:....||:..
  Fly   163 GFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMVYSLGSMMYWRSVAWCANVLPLLS 227

  Fly   566 LILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLK 630
            ::.:..|||||.|.:..|.|:||.:||.:|||.|...:.||..:  .|..|..:.:..|...:.:
  Fly   228 MVSISFIPETPAWLLRNGHEKRALQALSFLRGSEISAQKELNDM--KQRLAKERVTTKTNENIFQ 290

  Fly   631 L----NNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGI 691
            |    ..:|||.|.:.....|.|||...||||.|.:..:.|:..|.....|...:|..:...:..
  Fly   291 LCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFC 355

  Fly   692 VLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIP 756
            |::....|:.::.||.|...|...||..:.|.:...|.:|:..::...|.:.||: |:.....:|
  Fly   356 VVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFDQPKMSYDVFVGAGCLLGYII-FNTALMVMP 419

  Fly   757 WLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIY 821
            .:|:||:.||:|||..|....|......|:..|.|..|...:...|.|.:||...|:...|:.::
  Fly   420 GIMIGELFPARIRGRTAGGVFASMNVALFIFAKKFPALQAMLKMRGVFLVFGVSSFLLTAFMCLF 484

  Fly   822 VPETQGKTLEDIERKMMG------RVRRMSSVANIKPL 853
            .|||:|::||.||....|      |..|.....|::||
  Fly   485 QPETKGRSLEHIEDYFNGDNWLWFRRDRGYKTVNLQPL 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	136/454 (30%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	127/424 (30%)
CG4797	NP_726368.2	MFS	64..484	CDD:119392	127/422 (30%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	127/410 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I806
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I956
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.970