DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tret1-1 and Slc2a10

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_001102433.1	Gene:	Slc2a10 / 366251	RGDID:	1306552	Length:	536	Species:	Rattus norvegicus

Alignment Length:	558	Identity:	156/558 - (27%)
Similarity:	240/558 - (43%)	Gaps:	133/558 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 PTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSM-TDRNITSFEVTQDAGSWVGGIMPLA 449
            ||..|:      .|::|: ||.|..|:..|..|.||:.: .|..::..|.....||.:.|.. ||
  Rat     5 PTVLPL------CASVSL-LGGLTFGYELAVISGALLPLQLDFRLSCLEQELLVGSLLLGAF-LA 61

  Fly   450 GLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVY 514
            .|.||.    ||:..|||..||.:.|..:..||::..|.::..:|.||...||.:.::|::..:|
  Rat    62 SLVGGF----LIDCYGRRRAILGSNVVLLAGSLILGLAGSLPWLLLGRSSVGFAISLSSMACCIY 122

  Fly   515 LGETVQPEVRGTLGLLPTAFGNIGILLCF-----VAGSFMNWSMLAFLGAALPVPFLILMFLIPE 574
            :.|.|.|..||.|..|......:|||..:     :|||...|..: |..||.|.       |:..
  Rat   123 VSELVGPRQRGVLVSLYEVGITVGILFSYGLNYVLAGSPWGWRHM-FGWAAAPA-------LLQS 179

  Fly   575 TPRWFVGRGLE-ERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKLNN--LKP 636
            ...:|:..|.| ..||:.|..|:|.|.    ...||:::|         .|.|:|.:..:  ...
  Rat   180 LSLFFLPAGAEGTAARQDLIPLQGGET----SKLGLVKAQ---------YTFLDLFRAQDGMWSR 231

  Fly   637 LSISLGLMFFQQFSGINAVIFYTVQIFKDAG-----STIDGNLCTIIVGIVNFLATFIGIVLIDR 696
            ..:.|||:.|||.:|...|::|...||:..|     |.:   |.::.:|.|..:||.|...|:||
  Rat   232 TVVGLGLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAV---LASVGLGTVKVVATLIATGLVDR 293

  Fly   697 AGRKILLYVSDIAMVLTLFVLGGFFYC-----------------------------KTYGPDVSH 732
            .||:.||......|.|::..:|...:.                             :|..|.|.|
  Rat   294 VGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATSNTSQQVDLPQTPGLLVRTSLPPVLH 358

  Fly   733 ---------------------------------------------LGWLPLTCFVIYILGFSLGF 752
                                                         |.|..|.|.::|:..||.||
  Rat   359 TSGDQGQPVRSVTERPIHPVITASLGPALNIDSSVPTSPIPEHTLLCWSALVCMMVYVSAFSFGF 423

  Fly   753 GPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFF 817
            ||:.||::.||.|.:|||.|.:..::|||.....::.:|.||..|:|....|.|:|....:||.|
  Rat   424 GPVTWLVLSEIYPVEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAF 488

  Fly   818 VIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSF 855
            :.:.||||:|::|.:||::.  ::||.       ||||
  Rat   489 IYLLVPETKGQSLAEIEQQF--QMRRF-------PLSF 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	148/534 (28%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	138/508 (27%)
Slc2a10	NP_001102433.1	Sugar_tr	11..508	CDD:278511	147/526 (28%)
Slc2a10	NP_001102433.1	MFS	14..>330	CDD:119392	100/345 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750