DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and CG4607

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	534	Identity:	150/534 - (28%)
Similarity:	252/534 - (47%)	Gaps:	52/534 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 RGENIRHAVP--------FVRQITED--------GKPKLEVYRPTTNPIYIWTQVLAALSVSLGS 407
            :|:.....||        ..:..|:|        |:.:|.|.|          |.|.....:.|.
  Fly     2 KGQQEEQLVPPPAYKPTVVAKDTTKDSHAKEKPLGEGRLAVLR----------QELMVFLGNSGV 56

  Fly   408 LVVGFVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILA 472
            |..|.|.:..:..|..:.|.. ..|.:.:|..||...|..:|...||:.....::.:||::|||.
  Fly    57 LGSGMVVSMPAVTLNQLHDET-QPFWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILL 120

  Fly   473 TAVPFIVSSLLIACA-------VNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLL 530
            |.:..::..:|:..:       :....:|.||...|..:|:....:.||..|...|::||.| :|
  Fly   121 TNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRL-IL 184

  Fly   531 PTAFG-NIGILLCFVAGSFM--NWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKAL 592
            .|:.| ..||||.:..|.|:  |..::..:.....:...:|:|.:||:|.|.:.||.||||||:|
  Fly   185 GTSLGLASGILLMYCLGYFIRHNIQLIFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSL 249

  Fly   593 KWLRG---KEADVEPELK---GLMRSQADADRQASRNTMLELL--KLNNLKPLSISLGLMFFQQF 649
            ::.||   ||.|..||.:   ..|:..|||....:....|..:  :....||:.:......|||.
  Fly   250 RYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQA 314

  Fly   650 SGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAM-VLT 713
            .|:..:|.|.|||.:.||.|||..|..:::|:...:.|.....:.::.|||.....|...| ...
  Fly   315 CGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACM 379

  Fly   714 LFVLGGFFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATA 778
            |.:.||.::..|.|.    |.|||:.|.|.:|:..::|...:|:.|:.|:.|.:.||||:.:|..
  Fly   380 LLLAGGNWFPDTLGT----LHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIF 440

  Fly   779 FNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDI-ERKMMGRVR 842
            |.....|::.|.:.::..|:|....|..:..|.|:...|:.::||||:|:|||:: ||...|:..
  Fly   441 FGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFS 505

  Fly   843 RMSSVANIKPLSFN 856
            |..::.|:|.:..:
  Fly   506 RRLTIVNLKDVELH 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	137/469 (29%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	125/439 (28%)
CG4607	NP_572380.1	MFS	55..484	CDD:119392	125/434 (29%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	129/433 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4448
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800