DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tret1-1 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus

Alignment Length:	491	Identity:	145/491 - (29%)
Similarity:	226/491 - (46%)	Gaps:	58/491 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   397 VLAALSVSLGSLVVGF-VSAYTSPALVSMTDRNITSFEVTQDAGS-------W--VGGIMPLAGL 451
            |.|....::||...|: .....:|..:.....|.|..|..:|..|       |  ...|..:.|:
  Rat    13 VFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLLTTLWSLCVAIFSVGGM 77

  Fly   452 AGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIA---CAVNVAMVLCGRFLAGFCVGIASLSLPV 513
            .|..:.|..:...||||::|...:..|:...|:.   .|.:|.|::.||.:.|...|:.:..:|:
  Rat    78 IGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCTGFVPM 142

  Fly   514 YLGETVQPEVRGTLGLLPTAFGNIGIL------LCFVAGSFMNWSMLAFL--------GAALPVP 564
            |:||.....:||..|.|......:|||      |.|:.||...|..|..|        .||||
  Rat   143 YIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSAALP-- 205

  Fly   565 FLILMFLIPETPRW-FVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLEL 628
                  ..||:||: .:.|..|::|.:.|:.|.| ..||..|::. |:.::....|..:.|:|||
  Rat   206 ------FCPESPRFLLINRKEEDQATEILQRLWG-TPDVIQEIQE-MKDESIRMSQEKQVTVLEL 262

  Fly   629 LKL-NNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIV 692
            .|. :..:||.||:.|...|||||||||.:|:..||:||| ..:....||..|:||.:.|.:.:.
  Rat   263 FKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAG-VQEPIYATIGAGVVNTIFTVVSLF 326

  Fly   693 LIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTY-------GPDVSHLGWLPLTCFVIYILGFSL 750
            |::||||:.|..:.          |||...|..:       ..:...:.::.:...::|:..|.:
  Rat   327 LVERAGRRTLHMIG----------LGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAFFEI 381

  Fly   751 GFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGL 815
            |.|||||.::.|:.....|.:|.:||...||...|:|...|......:||: .|.:|.|.....|
  Rat   382 GPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAY-VFIIFAAFLVFFL 445

  Fly   816 FFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIK 851
            .|....||||:|:|.|||.|...|:.:.....|.::
  Rat   446 IFTFFKVPETKGRTFEDITRAFEGQAQSGKGSAGVE 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	140/471 (30%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	131/456 (29%)
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	142/473 (30%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	131/455 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740