Protein Alignment Tret1-1 and Slc2a4

DIOPT Version :10

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_001416984.1
• Gene: Slc2a4 / 25139
• RGDID: 2711
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 148/489 - (30%)
• Similarity: 222/489 - (45%)
• Gaps: 96/489 - (19%)

  Fly   374 TEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGF-VSAYTSPALVSMTDRNITSFEVTQD 437
            :|||:|..:  |.|      .|.|||..|..||||..|: :....:|..|.....|.|
  Rat    10 SEDGEPPQQ--RVT------GTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNAT------- 59

  Fly   438 AGSWVG-----------------------GIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIV 479
               |:|                       .|..:.|:......|.:.::|||:..:||..|..::
  Rat    60 ---WLGRQGPGGPDSIPQGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAVL 121

  Fly   480 SSLLIA---CAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILL 541
            ...|:.   .|.:..:::.||||.|...|:.|..:|:|:||.....:||.||.|......||||:
  Rat   122 GGALMGLANAAASYEILILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILV 186

  Fly   542 CFVAG--SFMN----WSMLAFLGAALPVPFLILMFLI---PETPRW-FVGRGLEERARKALKWLR 596
            ..|.|  |.:.    |.:|.   |...:|.|:.:.|:   ||:||: ::.|.||..|||:||.|.
  Rat   187 AQVLGLESMLGTATLWPLLL---AITVLPALLQLLLLPFCPESPRYLYIIRNLEGPARKSLKRLT 248

  Fly   597 GKEADVEPELKGLMRSQADADRQASRNTMLELLKL----NNLKPLSISLGLMFFQQFSGINAVIF 657
            | .|||...|..|    .|..|:..|...|.||:|    .:.:||.|::.|...||.||||||.:
  Rat   249 G-WADVSDALAEL----KDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFY 308

  Fly   658 YTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVS-------DIAMVLTLF 715
            |:..||:.|| .......||..|:||.:.|.:.::|::||||:.|..:.       .|.|.:.|.
  Rat   309 YSTSIFELAG-VEQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALL 372

  Fly   716 VLGGFFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFN 780
            :|...       |.:|::..:.:..||.:   |.:|.|||||.::.|:.....|.:|.:||...|
  Rat   373 LLERV-------PSMSYVSIVAIFGFVAF---FEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSN 427

  Fly   781 WFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVG 814
            |.|.|:|...||.:.|           |::.|.|
  Rat   428 WTCNFIVGMGFQYVAV-----------GSLPFAG 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	MFS_GLUT6_8_Class3_like	397..832	CDD:340916	141/466 (30%)
Slc2a4	NP_001416984.1	Interaction with SRFBP1. /evidence=ECO:0000250|UniProtKB:P14672	7..13		1/2 (50%)
		MFS_GLUT_Class1	26..451	CDD:340989	140/465 (30%)