Protein Alignment Tret1-1 and hmit-1.1

DIOPT Version :10

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 157/582 - (26%)
• Similarity: 253/582 - (43%)
• Gaps: 145/582 - (24%)

  Fly   385 RPTTNP-IYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPL 448
            :|...| :.::..:|||.|| :|..:.|:.::..|.|::.|.|               ..|:.|:
 Worm    14 KPAHTPKLGLFVYILAAASV-IGGFLFGYDTSVVSAAMLYMPD---------------APGLKPM 62

  Fly   449 ------------AGLA--GGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFL 499
                        .|:|  |.:..|...:|:|||..||..:..|.:.:|:.|.:||..|:|.||.|
 Worm    63 DTVWQEVLVSISPGMAAVGSLMSGTSSDYIGRRKVILGASAIFTIGALVCAASVNKIMLLVGRVL 127

  Fly   500 AGFCVGIASLSLPVYLGETVQPEVRGTL---GLLPTAFGNIGILLCFVAGSF-------MNWSML 554
            .|..:|.||:.:|||||||....|||.|   ..|..:||.  ::.....|:|       :.|.::
 Worm   128 LGIAIGFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQ--VVANITGGAFSYIDPYNVGWRLM 190

  Fly   555 AFLGAALP--VPFLILMFLIPETPRWFVGRGLEERARKAL-KWLRGKEADVEPELKGLMRSQADA 616
             |..||:|  :.|:..||| ||||||....|.|...|:.| |...|.:..||.|:..::....|.
 Worm   191 -FAFAAVPSIIQFVCFMFL-PETPRWLYENGFETETREVLEKVYNGDKEWVEYEMAEIIAFNEDQ 253

  Fly   617 DRQ-----ASRNTMLELLKLNN-LKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLC 675
            .::     ||...:..:||..: ||...|...|..|||.:|||.:::||..|.:.:|  |..|..
 Worm   254 AKENEKAHASGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSG--ISNNHT 316

  Fly   676 TI----IVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFF--------------- 721
            ||    ::.:.||:..|:.:.||::.||:|:...|...:||:|..:|..|
 Worm   317 TIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDSAATLPANQ 381

  Fly   722 ----------------------YCKTY----------------------GPDV------------ 730
                                  ||.|.                      .|:|
 Worm   382 YGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSSTGSCTNSNG 446

  Fly   731 ---SHLGW-----------LPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNW 781
               ::..|           ||:....:|:|.||.||..:||::..|..|...|.:..:::|..||
 Worm   447 SIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNW 511

  Fly   782 FCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRR 843
            ....::..|:..||..:|.:|||||:..:..:...|::..||||:|.::|::|...|.:.:|
 Worm   512 VFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEVEMLFMNKKQR 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	MFS_GLUT6_8_Class3_like	397..832	CDD:340916	151/556 (27%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	144/544 (26%)