Protein Alignment Tret1-1 and hmit-1.3

DIOPT Version :9

• Sequence 1: NP_610693.1
• Gene: Tret1-1 / 36248
• FlyBaseID: FBgn0050035
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 589
• Identity: 157/589 - (26%)
• Similarity: 254/589 - (43%)
• Gaps: 158/589 - (26%)

  Fly   385 RPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPL- 448
            ||:::|...|...:.|.|..:|..:.|:.:...|.|::.:.:               ..||.||
 Worm    17 RPSSDPKTGWFVYMLAFSAVIGGFLFGYDTGIVSAAMLYVPN---------------ASGIKPLD 66

  Fly   449 -----------AGLA--GGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLA 500
                       .|:|  |.:..||..::|||:..|:..:|.|.:.:::.|.|....::|.||.|.
 Worm    67 SVWQEIIVSITPGVAAIGSLCSGPGSDFLGRKKIIIGASVTFTIGAIICAAAWTKIILLIGRILL 131

  Fly   501 GFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFG---NIGILLC-FVAGSF-------MNWSML 554
            |..:|.||:.:|:|:.|.....:||.   |.|.|.   .:|:::. .:.|:|       :.|.::
 Worm   132 GLAIGFASMIVPIYVSEASPSHIRGK---LVTGFQLMITVGLVIANIIGGAFSYVDPDQVGWRLM 193

  Fly   555 AFLGAALP--VPFLILMFLIPETPRWFVGRGLEERARKAL--------KWLRGKEADV----EPE 605
             |..||:|  :.|:..:|| ||:|||....|....||:.|        :|:..:..::    |.|
 Worm   194 -FAFAAVPAIIQFVCFLFL-PESPRWLYEHGRTVEAREVLTRIYNGHTEWVDYEINEISFSYEEE 256

  Fly   606 LKGLMRSQADADRQASRNTMLELLKLNNL-KPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGST 669
            |:      |.|:...:..|::.:||..:: |.:.|...|..|||.||||.|::||..|.:.||
 Worm   257 LR------AKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAG-- 313

  Fly   670 IDGNLCTIIVGI----VNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFF--------- 721
            :..|..||.:.:    :|||.|||.|.|::|.||::||.||.|.::|.|..:|..|
 Worm   314 VKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLR 378

  Fly   722 ------YCKTYGPDVSHLG---------------------------------------------- 734
                  |...|.|.|.|..
 Worm   379 TFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGFCESKVAKKGYCLPFPSDDSSDYSATGI 443

  Fly   735 --------------W-----------LPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAAS 774
                          |           ||:...|.|:|.||.|:.|:||::..|..|...|.:|.|
 Worm   444 CEFSNLTNNGTDFEWEDTYCHTKFTVLPIIIMVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVS 508

  Fly   775 VATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMG 839
            |:||.||....:|:.||..|:.|...:|.|:::.....|.|.||..:||||:|.:::::|...|.
 Worm   509 VSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYSIDEVEMLFMT 573

  Fly   840 RVRR 843
            :..|
 Worm   574 KEER 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	154/577 (27%)
		MFS	401..822	CDD:119392	144/550 (26%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:421695	145/551 (26%)
		MFS	<190..>249	CDD:421695	18/60 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I2130
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2166
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820