DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and slc2a15a

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	XP_017950703.2	Gene:	slc2a15a / 100494397	XenbaseID:	XB-GENE-992550	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	543	Identity:	154/543 - (28%)
Similarity:	253/543 - (46%)	Gaps:	83/543 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 DSRKSRRLYEMDEMD-NKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSL 405
            |..|.:..:|::.:: .|:..|:.|......:|:..|              :.|..::||:..:|
Frog    11 DMEKQQGDWELERLNQQKQDRNMEHLDHETGKISRKG--------------FSWQLIMAAVVGAL 61

  Fly   406 G-SLVVGF-VSAYTSPALVSMTDRN---ITSFEVTQDAGS----W--VGGIMPLAGLAGGIAGGP 459
            | |.:.|: :|...:|::......|   ...:..|...|:    |  ...|..:.||.|.:...|
Frog    62 GSSFLYGYNLSVVNAPSVYIQELYNESWSARYNYTVSRGTISILWSVTVSIFAIGGLVGALIVIP 126

  Fly   460 LIEYLGRRNTILATAVPFIVSSLLIACAVNVA----MVLCGRFLAGFCVGIASLSLPVYLGETVQ 520
            ::.:|||:.|:|...| |.:::.|:....|||    |::.|||:.|...|||..:||:||.|...
Frog   127 MVNFLGRKGTMLLNNV-FAITAALLMSLSNVAGIPEMMILGRFIMGIDGGIALSTLPMYLNEVSP 190

  Fly   521 PEVRGTLGLLPTAFGNIGILLC---FVA---------GSFMNWSML-AFLGAALPVPFLILMFLI 572
            ..:||:||.: ||     ||:|   ||.         |....|..| .|:.....:..::|.| .
Frog   191 KHIRGSLGQV-TA-----ILICVGVFVGQVLGLPELFGKESQWPCLFGFIMIPALIQLVVLPF-F 248

  Fly   573 PETPRWFVGRGLE----ERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTML----ELL 629
            ||:||:.:   ||    :||.||.....|:. ||..:::.::     |:.:..||..|    ||.
Frog   249 PESPRYLL---LEKQDRKRAEKAFCIFLGRN-DVSQDIEDVL-----AETRIQRNLRLVSVPELF 304

  Fly   630 KLNNLKPLSIS-LGLMFFQQFSGINAVIFYTVQIFKDAGSTIDG-NLCTIIVGIVNFLATFIGIV 692
            |..::|...|: :..|...|..|:||:.|||..||.:||...|. ...|:..|.:..||:.|..:
Frog   305 KTRSVKWQIITVIVTMAAYQLCGLNAIWFYTNSIFSEAGIQPDKIPYITLSTGGIEILASVISGM 369

  Fly   693 LIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTYGPDVSHLGWLP---LTCFVIYILGFSLGFGP 754
            .::|.||:||| :....: :||| .|......|:   ..|..|:|   :.|.:..|..|.:|.|.
Frog   370 TVERLGRRILL-IGGFGL-MTLF-FGILTVSLTF---QHHAPWIPYISIVCILGVIASFCIGPGG 428

  Fly   755 IPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVI 819
            ||::::||......|.:|..:|.:.||...|.|...|..:...:|.: .|.:|.|||..|..::.
Frog   429 IPFVLVGEFFQQSQRPAAFMIAGSVNWISNFAVGLLFPLIQEGLGNY-CFLIFAAICLAGTLYLY 492

  Fly   820 IYVPETQGKTLEDIER---KMMG 839
            ..:|||:.||..:|::   ||.|
Frog   493 FILPETKNKTFSEIDQAFAKMNG 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	142/491 (29%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	134/461 (29%)
slc2a15a	XP_017950703.2	MFS_GLUT_Class2	55..506	CDD:340990	141/474 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000