DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tret1-1 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	XP_038967504.1	Gene:	Slc2a7 / 100362644	RGDID:	1583902	Length:	525	Species:	Rattus norvegicus

Alignment Length:	504	Identity:	158/504 - (31%)
Similarity:	243/504 - (48%)	Gaps:	58/504 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 TQVLAALSVSLGSLV--------------VGFVSAYTSPALVSMTDRNITSFE---VTQDAGS-- 440
            |.||..||.:.||..              ||..|.:.....|..:..|.|.||   ...|..:
  Rat    22 TLVLTTLSAAFGSAFQYGYNIAVINTPHKVGTSSGWGPVFQVLKSFYNDTYFERHGTFMDENTLL 86

  Fly   441 --W--VGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVA----MVLCGR 497
              |  ...:.||.||.|.:..|.::...||:.|:|...| |.::|.::..|...|    :::..|
  Rat    87 LLWSCTVSMFPLGGLLGSLVVGMMVNKWGRKRTLLINNV-FAITSAVLMGASKAARAFELIIFSR 150

  Fly   498 FLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLC------FVAGSFMNWS-MLA 555
            .:.|.|.|||..:||:||||.....:|||||.:...|...|:||.      .:.|:...|. :||
  Rat   151 VMVGICAGIAYSTLPMYLGELAPQNLRGTLGTMTEVFVIFGVLLAQIFSLQTILGNATGWPILLA 215

  Fly   556 FLGAALPVPFLILMFLIPETPRW-FVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQ 619
            ..|....:..|.|.| .||:||: .:.:|.||..|:||:.|||...:||.|::. ||::...::.
  Rat   216 LTGVPALIQLLSLPF-FPESPRYTLIEKGDEETTRQALRRLRGHSYNVEAEMEE-MRTEERTEKA 278

  Fly   620 ASRNTMLELLKLNNLKPLSISL-GLMFFQQFSGINAVIFYTVQIFKDAG-STIDGNLCTIIVGIV 682
            ..|.::|.|.....|:...||: .||..||.||||||.:|...|:..|| ........|:..|::
  Rat   279 EGRLSVLNLFTFRPLRWQLISIVVLMAGQQLSGINAVNYYADIIYTSAGVDPTQSQYVTLGSGVI 343

  Fly   683 NFLATFIGIVLIDRAGRKILL-----YVSDIAMVLTLFVLGGFFYCKTYGPDVSHLGWLPLTCFV 742
            |.:.|.:...:|:|.||:|||     ......:|||:.:|     .::..|::|:||   :.|..
  Rat   344 NLVMTLVSAFIIERLGRRILLLSGYGICGSACLVLTVALL-----LQSTVPELSYLG---IICVF 400

  Fly   743 IYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLF 807
            .||:|.|:|..|:|.::..||:....|.:|.:|..|.:|...|:|..||..:.||:||: :|.:|
  Rat   401 SYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGAVHWLTNFIVGLTFPSIQVAIGAY-SFLIF 464

  Fly   808 GAICFVGLFFVIIYVPETQGKTLEDIE---RKMMG-RVRRMSSVANIKP 852
            ..||.:...::.:.:|||:|||..:|.   .|..| .|.....|...||
  Rat   465 AGICLLTAAYIYVVIPETKGKTFVEINCIFAKRNGVEVSEEKEVTTAKP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	151/479 (32%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	142/462 (31%)
Slc2a7	XP_038967504.1	MFS_GLUT_Class2	26..490	CDD:340990	148/475 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337727
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840