DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-1 and slc2a7

DIOPT Version :9

Sequence 1:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_001120033.1	Gene:	slc2a7 / 100144999	XenbaseID:	XB-GENE-5811422	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	526	Identity:	132/526 - (25%)
Similarity:	215/526 - (40%)	Gaps:	118/526 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 KLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSF---------EVT 435
            |.:..||..:.::     ||..:|.:|.   .|...| :.::::...|.|..|         :..
Frog     9 KKQTSRPPISRLF-----LAVCAVGIGG---AFQYGY-NVSIINAPTRQIQQFINNTWYSRHQSN 64

  Fly   436 QDAG------SWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN---VA 491
            .:.|      |.:..:..|.||.|...||.|.:.|||:.|:|...|..|:::.|:..|..   ..
Frog    65 LEEGWLTLIWSVIASVFTLGGLLGTHIGGHLADKLGRKKTLLMNNVLAILAAFLMGIAYPSGCFE 129

  Fly   492 MVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRG--TLGLLPTAFGNI------GILLCFVAGSF 548
            :::.||.:.|...||.....|:||||.....:||  |:|:.....|.|      |:...|..|.
Frog   130 LLIVGRLIIGINAGIGLCVQPLYLGEIAPRHIRGLTTVGMNIFLTGGIFTGQLVGLRELFGGGD- 193

  Fly   549 MNWSMLAFLGAALP---VPFLILMFLI---PETPRWFVGRGLEE-RARKALKWLRGKEADVEPEL 606
             ||..|      ||   :|.:|.:..:   ||:||:.:....:| :.:||||.|.|.| ..:||:
Frog   194 -NWYFL------LPTCCIPAIIQLASLPWFPESPRYLLIENKDEYQCQKALKMLYGSE-HYQPEM 250

  Fly   607 KGLMRSQADADRQASRNTMLELLKLNNLKPLSI-------------------SLGLMFFQQFSGI 652
            ..:::               |...||..||.:|                   ::|    ||.|||
Frog   251 DDILK---------------ESCALNGEKPKTIFQLFSDRTVRWQLVIIILTNIG----QQLSGI 296

  Fly   653 NAVIFYTVQIFKDAGSTIDGN---LCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTL 714
            ||:.||...:|..||  |..|   ..|:..|:...|......:|||.|||:||
Frog   297 NAIYFYAAYVFTKAG--IPANNIPYVTLGTGLCECLTALTCGLLIDIAGRRIL------------ 347

  Fly   715 FVLGGF----FYCK------TYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIR 769
             ::||:    |:|.      |:......:.:|.::....:||.|.||.|.:...:..|:.....|
Frog   348 -IIGGYTLMAFWCTILTLTLTFQDVYPWIPYLSMSAVFAFILSFGLGPGGVTNTLTAELFTQSSR 411

  Fly   770 GSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIE 834
            .:|..::.:..|...|.:...|..|...:..: .|..|...|.:...|:...||||:.|:..:|:
Frog   412 SAAFRISGSVGWITFFTIGMIFPFLVNGLNQY-CFLFFFVECLLTASFIFFIVPETKNKSFLEIK 475

  Fly   835 RKMMGR 840
            ::...|
Frog   476 KEFQKR 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	129/515 (25%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	120/485 (25%)
slc2a7	NP_001120033.1	MFS_GLUT_Class2	23..474	CDD:340990	126/498 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910