Protein Alignment CG9003 and AMN1

DIOPT Version :10

• Sequence 1: NP_001097271.1
• Gene: CG9003 / 36244
• FlyBaseID: FBgn0033639
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_009716.1
• Gene: AMN1 / 852455
• SGDID: S000000362
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 569
• Identity: 121/569 - (21%)
• Similarity: 201/569 - (35%)
• Gaps: 154/569 - (27%)

  Fly   108 RQHSSGSNSRQHSSSSSNSNSS----NISPPPSSSSSSRS--------NNNNNNHSSNIISGFCS 160
            |..|:||..|.....|..|..:    .:||.||.:|....        ....:.|.|:...|
Yeast     5 RVSSNGSFKRGRDIQSLESPCTRPLKKMSPSPSFTSLKMEKPFKDIVRKYGGHLHQSSYNPG--- 66

  Fly   161 TIWRSATFGSATPVINPLPAVSINPKIMESS------SDSCSLSSSTTPDVGLADQQRNMAGSAQ 219
                    .|...::.|..::..:...::||      ..||:...||.....|.:.....|.:..
Yeast    67 --------SSKVELVRPDLSLKTDQSFLQSSVQTTPNKKSCNEYLSTPEATPLKNTATENAWATS 123

  Fly   220 DQSEDQSQTFLGATELDDELIKQLPKEVLLRVFSYLD---------------------------- 256
            ......|.:.:..||:         |.:|:..||.|.
Yeast   124 RVVSASSLSIVTPTEI---------KNILVDEFSELKLGQPLTAQHQRSHAVFEIPEIVENIIKM 179

  Fly   257 VVSLCRCAQVCKYWNVLALDGSSWQKINLF--DFQR---------DIEGPVIENISQRCRGFL-- 308
            :||| ..|.:.|....|..:..|::...|.  |.:|         .:..|.:....::.:|.|
Yeast   180 IVSL-ESANIPKERPCLRRNPQSYEHSLLMYKDEERAKKAWSAAQQLRDPPLVGHKEKKQGALFS 243

  Fly   309 -----------------KSLSLRGCQSVGD-----QSVRTLANHCHNIEHLDLSDCKKITDISTQ 351
                             |||..:...:..:     |....:....|.|.|    ...::|....:
Yeast   244 CMMVNRLWLNVTRPFLFKSLHFKSVHNFKEFLRTSQETTQVMRPSHFILH----KLHQVTQPDIE 304

  Fly   352 SISRY-CSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKF 415
            .:||. |..|..:..:.|..||           |.|     ||...:.            ||.|.
Yeast   305 RLSRMECQNLKWLEFYVCPRIT-----------PPL-----SWFDNLH------------KLEKL 341

  Fly   416 SSKGCKQINDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCAD---LTD 477
            ...|.|.|:||.::.|::..|:|..|.|.:|:.::||.:..:|.||.||:...:.:...   :|.
Yeast   342 IIPGNKNIDDNFLLRLSQSIPNLKHLVLRACDNVSDSGVVCIALNCPKLKTFNIGRHRRGNLITS 406

  Fly   478 LTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGR-NCKYLERMDLEECSQITDLTLAHL--ATGC 539
            ::|::|.::.. :.|:..:|| :..|.|.....| |.|.:||:.|..|..:||.:|..|  ....
Yeast   407 VSLVALGKYTQ-VETVGFAGC-DVDDAGIWEFARLNGKNVERLSLNSCRLLTDYSLPILFALNSF 469

  Fly   540 PSLEKLTLSHCELITDDGIRH-----LTTGSCAAEILSVLELDNCPLIT 583
            |:|..|.:.:.:.|||  :||     |...|..|.||    ::.|..||
Yeast   470 PNLAVLEIRNLDKITD--VRHFVKYNLWKKSLDAPIL----IEACERIT 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box_FBXL2-like	237..281	CDD:438887	12/71 (17%)
		leucine-rich repeat	280..307	CDD:275381	4/37 (11%)
		AMN1	<308..453	CDD:187754	35/169 (21%)
		leucine-rich repeat	308..327	CDD:275381	5/42 (12%)
		leucine-rich repeat	334..359	CDD:275381	6/25 (24%)
		leucine-rich repeat	360..385	CDD:275381	4/24 (17%)
		leucine-rich repeat	386..411	CDD:275381	3/24 (13%)
		AMN1	<409..586	CDD:187754	56/186 (30%)
		leucine-rich repeat	412..437	CDD:275381	8/24 (33%)
		leucine-rich repeat	438..463	CDD:275381	9/24 (38%)
		leucine-rich repeat	464..515	CDD:275381	11/54 (20%)
		leucine-rich repeat	516..541	CDD:275381	8/26 (31%)
		leucine-rich repeat	542..561	CDD:275381	7/23 (30%)
		leucine-rich repeat	571..595	CDD:275381	4/13 (31%)
		leucine-rich repeat	596..621	CDD:275381
AMN1	NP_009716.1	AMN1	285..509	CDD:187754	68/263 (26%)
		leucine-rich repeat	314..337	CDD:275381	8/50 (16%)
		leucine-rich repeat	338..363	CDD:275381	8/24 (33%)
		leucine-rich repeat	364..389	CDD:275381	9/24 (38%)
		leucine-rich repeat	390..417	CDD:275381	4/26 (15%)
		leucine-rich repeat	418..443	CDD:275381	7/25 (28%)
		leucine-rich repeat	444..471	CDD:275381	8/26 (31%)
		leucine-rich repeat	472..493	CDD:275381	7/22 (32%)