DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9003 and SKP2B

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001185415.1	Gene:	SKP2B / 844036	AraportID:	AT1G77000	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	367	Identity:	105/367 - (28%)
Similarity:	184/367 - (50%)	Gaps:	51/367 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   241 KQLPKEVLLRVFSYLD--VVSLCRCAQVCKYW-NVLALD----GSSWQKINLFDFQRDIEGPVIE 298
            |.:|.|:|:::.:.:|  .|.:..|  :|..| :.::|.    ..||.|.|:......:....::
plant    29 KDIPVELLMKILNLVDDRTVIIASC--ICSGWRDAVSLGLTRLSLSWCKKNMNSLVLSLAPKFVK 91

  Fly   299 NISQRCRGFLKSLSLRGCQ-SVGDQSVRTLANHCHNIEHLDLSDCKKITDISTQSISRYCSKLTA 362
                     |::|.||..: .:.|.:|..:|||||.::.||||...||||.|..|::|.|:.||.
plant    92 ---------LQTLVLRQDKPQLEDNAVEAIANHCHELQDLDLSKSSKITDHSLYSLARGCTNLTK 147

  Fly   363 INLHSCSNITDNSLKYLSDGCPNLMEINVSWC-HLISENGVEALARGCVKLRKFSSKGCKQINDN 426
            :||..|::.:|.:|.:|:..|..|..:|:..| ..:|:|.::|:...|.:|:..:...|:.|:|:
plant   148 LNLSGCTSFSDTALAHLTRFCRKLKILNLCGCVEAVSDNTLQAIGENCNQLQSLNLGWCENISDD 212

  Fly   427 AIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCADLTDLTLLSLSQHNHLLN 491
            .:|.||..||||..|:|.||..|||.|:..||..|..|:.|.:..|.::||..:.||:|
plant   213 GVMSLAYGCPDLRTLDLCSCVLITDESVVALANRCIHLRSLGLYYCRNITDRAMYSLAQ------ 271

  Fly   492 TLEVSGCRNFTDIGFQALGRNCKY----LERMDLEECSQITDLTLAHLATGCPSLEKLTLSHCEL 552
                ||.:|..:: ::|:.:. |:    |..:::.:|:.:|...:..:....|:|...:..|..:
plant   272 ----SGVKNKHEM-WRAVKKG-KFDEEGLRSLNISQCTYLTPSAVQAVCDTFPALHTCSGRHSLV 330

  Fly   553 ITDDGIRHLTTGSCAAEILSVLELDNCPLITDRTLEHLVSCH 594
            ::  |..:|.:..||           |.|...||  |.|..|
plant   331 MS--GCLNLQSVHCA-----------CILQAHRT--HTVYPH 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	13/50 (26%)
		leucine-rich repeat	280..307	CDD:275381	3/26 (12%)
		AMN1	<308..453	CDD:187754	57/146 (39%)
		leucine-rich repeat	308..327	CDD:275381	6/19 (32%)
		leucine-rich repeat	334..359	CDD:275381	12/24 (50%)
		leucine-rich repeat	360..385	CDD:275381	9/24 (38%)
		leucine-rich repeat	386..411	CDD:275381	7/25 (28%)
		AMN1	<409..586	CDD:187754	48/180 (27%)
		leucine-rich repeat	412..437	CDD:275381	8/24 (33%)
		leucine-rich repeat	438..463	CDD:275381	12/24 (50%)
		leucine-rich repeat	464..515	CDD:275381	12/50 (24%)
		leucine-rich repeat	516..541	CDD:275381	3/24 (13%)
		leucine-rich repeat	542..561	CDD:275381	3/18 (17%)
		leucine-rich repeat	571..595	CDD:275381	7/24 (29%)
		leucine-rich repeat	596..621	CDD:275381
SKP2B	NP_001185415.1	F-box	28..63	CDD:395521	9/35 (26%)
		leucine-rich repeat	66..91	CDD:275381	4/24 (17%)
		leucine-rich repeat	92..118	CDD:275381	10/25 (40%)
		AMN1	<115..264	CDD:187754	57/148 (39%)
		leucine-rich repeat	119..144	CDD:275381	12/24 (50%)
		leucine-rich repeat	145..170	CDD:275381	9/24 (38%)
		leucine-rich repeat	171..197	CDD:275381	7/25 (28%)
		leucine-rich repeat	198..223	CDD:275381	8/24 (33%)
		leucine-rich repeat	224..249	CDD:275381	12/24 (50%)
		leucine-rich repeat	250..272	CDD:275381	8/31 (26%)
		leucine-rich repeat	294..319	CDD:275381	3/24 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920