DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9003 and EBF2

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_197917.1	Gene:	EBF2 / 832607	AraportID:	AT5G25350	Length:	623	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	129/518 - (24%)
Similarity:	205/518 - (39%)	Gaps:	116/518 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 SSSDSCSLSSS------TTPDVGLADQQR-NMAGSAQDQSEDQSQTFLGATELDDELIKQLPKEV 247
            |..:.|.|..|      :.|.|....::| .:|.::.....::.||          .|..||:|.
plant     8 SGDEDCLLGGSMYLSPGSCPGVYYPARKRLRVAATSFYSGFEEKQT----------SIDVLPEEC 62

  Fly   248 LLRVFSYL---DVVSLCRCAQVCKYW-NVLA------LDGSSWQKINLFD--FQRDIEGPVIEN- 299
            |..:...|   ...|.|.|  |.|:| |:|:      ::.||.|.:...:  ..|.:||....:
plant    63 LFEILRRLPSGQERSACAC--VSKHWLNLLSSISRSEVNESSVQDVEEGEGFLSRSLEGKKATDL 125

  Fly   300 ------ISQRCRGFLKSLSLRGC---QSVGDQSVRTLANHCHNIEHLDLSDCKKITDISTQSISR 355
                  :....||.|..|.:||.   ..|.|..:..:|:.|.::..:.|.:...::|:....|:|
plant   126 RLAAIAVGTSSRGGLGKLQIRGSGFESKVTDVGLGAVAHGCPSLRIVSLWNLPAVSDLGLSEIAR 190

  Fly   356 YCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKFSSKGC 420
            .|..:..::|..|..|||:.|..:::.|.||.::.:..|..:...|:.|:||.||.||..|.:.|
plant   191 SCPMIEKLDLSRCPGITDSGLVAIAENCVNLSDLTIDSCSGVGNEGLRAIARRCVNLRSISIRSC 255

  Fly   421 KQINDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKC---------ADLT 476
            .:|.|..:..|...               ..|.:.::     |||.|.||..         |.:|
plant   256 PRIGDQGVAFLLAQ---------------AGSYLTKV-----KLQMLNVSGLSLAVIGHYGAAVT 300

  Fly   477 DLTLLSLSQHNH-------------LLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQIT 528
            ||.|..|...|.             .|.:|.|..||..||:|.:|:|..|..|:.:.|.:|..::
plant   301 DLVLHGLQGVNEKGFWVMGNAKGLKKLKSLSVMSCRGMTDVGLEAVGNGCPDLKHVSLNKCLLVS 365

  Fly   529 DLTLAHLATGCPSLEKLTLSHCELITDDGI----------------------------RHLTTGS 565
            ...|..||....|||.|.|..|..|...|:                            ..|.:.|
plant   366 GKGLVALAKSALSLESLKLEECHRINQFGLMGFLMNCGSKLKAFSLANCLGISDFNSESSLPSPS 430

  Fly   566 CAAEILSVLELDNCPLITDRTLEHLVS-CHNLQRIELFDCQLITRTAIRKL--KNHLPNIKVH 625
            |::  |..|.:..||...|.:|..|.. ||.||.:||.....:|...:|:|  .|::..:||:
plant   431 CSS--LRSLSIRCCPGFGDASLAFLGKFCHQLQDVELCGLNGVTDAGVRELLQSNNVGLVKVN 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	17/54 (31%)
		leucine-rich repeat	280..307	CDD:275381	5/35 (14%)
		AMN1	<308..453	CDD:187754	36/147 (24%)
		leucine-rich repeat	308..327	CDD:275381	6/21 (29%)
		leucine-rich repeat	334..359	CDD:275381	5/24 (21%)
		leucine-rich repeat	360..385	CDD:275381	7/24 (29%)
		leucine-rich repeat	386..411	CDD:275381	7/24 (29%)
		AMN1	<409..586	CDD:187754	56/226 (25%)
		leucine-rich repeat	412..437	CDD:275381	7/24 (29%)
		leucine-rich repeat	438..463	CDD:275381	1/24 (4%)
		leucine-rich repeat	464..515	CDD:275381	23/72 (32%)
		leucine-rich repeat	516..541	CDD:275381	6/24 (25%)
		leucine-rich repeat	542..561	CDD:275381	7/46 (15%)
		leucine-rich repeat	571..595	CDD:275381	8/24 (33%)
		leucine-rich repeat	596..621	CDD:275381	8/26 (31%)
EBF2	NP_197917.1	F-box	54..>92	CDD:279040	14/39 (36%)
		AMN1	<138..268	CDD:187754	37/129 (29%)
		leucine-rich repeat	169..194	CDD:275381	5/24 (21%)
		leucine-rich repeat	195..220	CDD:275381	7/24 (29%)
		leucine-rich repeat	221..246	CDD:275381	7/24 (29%)
		leucine-rich repeat	247..278	CDD:275381	8/50 (16%)
		leucine-rich repeat	279..326	CDD:275381	12/46 (26%)
		leucine-rich repeat	327..352	CDD:275381	11/24 (46%)
		leucine-rich repeat	353..378	CDD:275381	6/24 (25%)
		leucine-rich repeat	379..402	CDD:275381	7/22 (32%)
		leucine-rich repeat	406..459	CDD:275381	11/54 (20%)
		leucine-rich repeat	407..433	CDD:275381	3/25 (12%)
		AMN1	435..>582	CDD:187754	18/57 (32%)
		leucine-rich repeat	460..511	CDD:275381	10/32 (31%)
		leucine-rich repeat	487..512	CDD:275381	2/5 (40%)
		leucine-rich repeat	514..537	CDD:275381
		leucine-rich repeat	540..566	CDD:275381
		leucine-rich repeat	567..595	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010