DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9003 and AT5G01720

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_568094.2	Gene:	AT5G01720 / 831688	AraportID:	AT5G01720	Length:	665	Species:	Arabidopsis thaliana

Alignment Length:	586	Identity:	142/586 - (24%)
Similarity:	230/586 - (39%)	Gaps:	143/586 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 ISPPPSSSSSSRSNNNNNNHSSNIISGFCSTIWR--SATFGSATPVINPLPAVSINPKIMESSSD 193
            |||.||...|              .|..|.:.::  |...||..|:.:     ...|:|:....:
plant    28 ISPNPSDLKS--------------FSLTCKSFYQLESKHRGSLKPLRS-----DYLPRILTRYRN 73

  Fly   194 SCSLSSSTTPDVGLADQQRNMAG-------SAQDQSEDQSQTFLG------------------AT 233
            :..|..:..|.|  .|...::.|       .:.|.|...|.:..|                  ||
plant    74 TTDLDLTFCPRV--TDYALSVVGCLSGPTLRSLDLSRSGSFSAAGLLRLALKCVNLVEIDLSNAT 136

  Fly   234 ELDDELIKQLPKEVLLRVFSYLDVVSLCRCAQV-----------CKYWNVLALDGSSW------- 280
            |:.|     ....|:....| |:.:.|.||..:           ||..|.::|   .|
plant   137 EMRD-----ADAAVVAEARS-LERLKLGRCKMLTDMGIGCIAVGCKKLNTVSL---KWCVGVGDL 192

  Fly   281 ---------QKINLFDFQ-RDIEGPVIENISQRCRGFLKSLSLRGCQSVGDQSVRTL-------- 327
                     :.|...|.. ..|.|..:.:|.:  ...|:.|.|.||..|.|.|:::|
plant   193 GVGLLAVKCKDIRTLDLSYLPITGKCLHDILK--LQHLEELLLEGCFGVDDDSLKSLRHDCKSLK 255

  Fly   328 ---ANHCHNIEH---------------LDLSDCKKITDISTQSISRYCSKLTAINLHSCSNITDN 374
               |:.|.|:.|               ||||.|..:..:...|..:..|.|.:|.|..|| :|.:
plant   256 KLDASSCQNLTHRGLTSLLSGAGYLQRLDLSHCSSVISLDFASSLKKVSALQSIRLDGCS-VTPD 319

  Fly   375 SLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKFSSKGCKQINDNAIMCLAKYCPDLM 439
            .||.:...|.:|.|:::|.|..:::.|:.:|......|||.....|::::..:|..:|..||.|:
plant   320 GLKAIGTLCNSLKEVSLSKCVSVTDEGLSSLVMKLKDLRKLDITCCRKLSRVSITQIANSCPLLV 384

  Fly   440 VLNLHSCETITDSSIRQLAANCHKLQKLCVSKCADLTD-----------LTLLSLSQHNHLLNTL 493
            .|.:.||..::..:...:...|..|::|      ||||           .:.||||       :|
plant   385 SLKMESCSLVSREAFWLIGQKCRLLEEL------DLTDNEIDDEGLKSISSCLSLS-------SL 436

  Fly   494 EVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLTLAHLATGCPSLEKLTLSHCELITDDGI 558
            ::..|.|.||.|...:|..|..|..:||.....|||:.::.:|.||..||.:.:|:|:.|||..:
plant   437 KLGICLNITDKGLSYIGMGCSNLRELDLYRSVGITDVGISTIAQGCIHLETINISYCQDITDKSL 501

  Fly   559 RHLTTGSCAAEILSVLELDNCPLITDRTLEHL-VSCHNLQRIELFDCQLITRTAIRKLKNHLPNI 622
              ::...|:  :|...|...||.||.:.|..: |.|..|.:::|..|..|....:..|.:...|:
plant   502 --VSLSKCS--LLQTFESRGCPNITSQGLAAIAVRCKRLAKVDLKKCPSINDAGLLALAHFSQNL 562

  Fly   623 K 623
            |
plant   563 K 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	12/71 (17%)
		leucine-rich repeat	280..307	CDD:275381	6/43 (14%)
		AMN1	<308..453	CDD:187754	47/170 (28%)
		leucine-rich repeat	308..327	CDD:275381	8/18 (44%)
		leucine-rich repeat	334..359	CDD:275381	7/39 (18%)
		leucine-rich repeat	360..385	CDD:275381	9/24 (38%)
		leucine-rich repeat	386..411	CDD:275381	6/24 (25%)
		AMN1	<409..586	CDD:187754	54/187 (29%)
		leucine-rich repeat	412..437	CDD:275381	7/24 (29%)
		leucine-rich repeat	438..463	CDD:275381	5/24 (21%)
		leucine-rich repeat	464..515	CDD:275381	18/61 (30%)
		leucine-rich repeat	516..541	CDD:275381	9/24 (38%)
		leucine-rich repeat	542..561	CDD:275381	7/18 (39%)
		leucine-rich repeat	571..595	CDD:275381	9/24 (38%)
		leucine-rich repeat	596..621	CDD:275381	5/24 (21%)
AT5G01720	NP_568094.2	AMN1	60..>201	CDD:187754	26/156 (17%)
		leucine-rich repeat	74..93	CDD:275381	4/20 (20%)
		leucine-rich repeat	101..126	CDD:275381	4/24 (17%)
		leucine-rich repeat	127..151	CDD:275381	5/28 (18%)
		leucine-rich repeat	152..172	CDD:275381	4/19 (21%)
		leucine-rich repeat	178..203	CDD:275381	3/27 (11%)
		AMN1	196..372	CDD:187754	44/178 (25%)
		leucine-rich repeat	204..247	CDD:275381	13/44 (30%)
		leucine-rich repeat	254..279	CDD:275381	4/24 (17%)
		leucine-rich repeat	280..330	CDD:275381	16/50 (32%)
		AMN1	<328..500	CDD:187754	54/184 (29%)
		leucine-rich repeat	331..356	CDD:275381	6/24 (25%)
		leucine-rich repeat	357..382	CDD:275381	7/24 (29%)
		leucine-rich repeat	383..408	CDD:275381	5/24 (21%)
		leucine-rich repeat	409..458	CDD:275381	18/61 (30%)
		AMN1	<441..567	CDD:187754	40/127 (31%)
		leucine-rich repeat	459..484	CDD:275381	9/24 (38%)
		leucine-rich repeat	485..507	CDD:275381	7/23 (30%)
		leucine-rich repeat	510..535	CDD:275381	9/24 (38%)
		leucine-rich repeat	536..561	CDD:275381	5/24 (21%)
		leucine-rich repeat	562..585	CDD:275381	1/2 (50%)
		leucine-rich repeat	586..609	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101086
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910