DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9003 and VFB3

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_567316.1	Gene:	VFB3 / 826171	AraportID:	AT4G07400	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	114/492 - (23%)
Similarity:	184/492 - (37%)	Gaps:	106/492 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 DQQRNMAGSAQDQSEDQSQTFL------------GATELDDELIKQLPKEVLLRVFSYLDVVSLC 261
            :..|...|.:..:......||.            ||.|..| .|..||.|.|..:|..|....|.
plant    32 EPHRRRMGQSTSKFRRSKTTFTSPVLPNLREQNSGADEPYD-YISNLPDECLSLIFQSLTCADLK 95

  Fly   262 RCAQVCKYWNVLALDGSSWQKINLFDFQRDIEGPVIENISQRCRGFLKSLSLRGCQSVG--DQSV 324
            ||:.||:.|  |.::|....:::| ..|.|:.. ||.::..|.....|.:.....:|:|  |.:.
plant    96 RCSLVCRRW--LTIEGQCRHRLSL-KAQSDLIS-VIPSLFTRFDSVTKLVLRSDRRSLGICDNAF 156

  Fly   325 RTLANHCHNIEHLDLSDCKKITDISTQSISRYCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEI 389
            ..::..|.|:..|.|..|.:|:|:.....:..|..|..::..|| ......:..|.:.|..|.|:
plant   157 VMISVRCRNLTRLKLRGCPEISDLGIIGFTENCRSLKKVSFGSC-GFGVKGMNALLNTCLGLEEL 220

  Fly   390 NVSWCHLISENGVEALARG---------CVK-----------------LRKFSSKGCK------- 421
            :|.....|.. |.|.:..|         |:|                 ||......|.
plant   221 SVKRLRGIGA-GAELIGPGGAAGSLKVICLKELHNGQCFAPLLSGAKGLRILKIFRCSGDWDRVF 284

  Fly   422 ------------------QINDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLC 468
                              |::|..:..|:| |..:.||:|......|:..:..:|..|..|:||.
plant   285 EAVRDKVNAIVEIHLERIQMSDLGLTALSK-CSGVEVLHLVKTPDCTNVGLALVAERCKLLRKLH 348

  Fly   469 VS--KCADLTDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLT 531
            :.  |...:.|..|:.::::...|..|.:.|. |.|.:..:|:..||..|||:.|.....:.|..
plant   349 IDGWKTNRIGDEGLIVVAKYCWNLQELVLIGV-NPTKLSLEAIVSNCLNLERLALCGSDTVGDTE 412

  Fly   532 LAHLATGCPSLEKLTLSHCELITDDGIRHLTTGSCAAEILSVLELDNCPLITDRTLEHLVSCHNL 596
            |..:|..|.:|.||.:.:|. ||||||:.|..|                            |.||
plant   413 LCCIAEKCLALRKLCIKNCP-ITDDGIKALGNG----------------------------CPNL 448

  Fly   597 QRIELFDCQLITRTAIRKLKNHLPNIKVHAYFAPGTP 633
            .::::..|:.:|......|:.....:.|: ..||.||
plant   449 LKVKVKKCRGVTTQGADLLRKRRALLVVN-LDAPETP 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	15/44 (34%)
		leucine-rich repeat	280..307	CDD:275381	6/26 (23%)
		AMN1	<308..453	CDD:187754	38/197 (19%)
		leucine-rich repeat	308..327	CDD:275381	4/20 (20%)
		leucine-rich repeat	334..359	CDD:275381	6/24 (25%)
		leucine-rich repeat	360..385	CDD:275381	5/24 (21%)
		leucine-rich repeat	386..411	CDD:275381	8/33 (24%)
		AMN1	<409..586	CDD:187754	50/220 (23%)
		leucine-rich repeat	412..437	CDD:275381	8/49 (16%)
		leucine-rich repeat	438..463	CDD:275381	6/24 (25%)
		leucine-rich repeat	464..515	CDD:275381	14/52 (27%)
		leucine-rich repeat	516..541	CDD:275381	8/24 (33%)
		leucine-rich repeat	542..561	CDD:275381	10/18 (56%)
		leucine-rich repeat	571..595	CDD:275381	1/23 (4%)
		leucine-rich repeat	596..621	CDD:275381	4/24 (17%)
VFB3	NP_567316.1	F-box-like	74..>104	CDD:289689	12/29 (41%)
		leucine-rich repeat	89..114	CDD:275381	9/26 (35%)
		leucine-rich repeat	115..165	CDD:275381	11/51 (22%)
		AMN1	<146..>226	CDD:187754	19/80 (24%)
		leucine-rich repeat	166..191	CDD:275381	6/24 (25%)
		leucine-rich repeat	192..216	CDD:275381	5/24 (21%)
		leucine-rich repeat	268..293	CDD:275381	3/24 (13%)
		leucine-rich repeat	294..317	CDD:275381	5/23 (22%)
		leucine-rich repeat	318..343	CDD:275381	6/24 (25%)
		AMN1	<340..>463	CDD:187754	40/152 (26%)
		leucine-rich repeat	344..371	CDD:275381	6/26 (23%)
		leucine-rich repeat	372..396	CDD:275381	8/24 (33%)
		leucine-rich repeat	397..422	CDD:275381	8/24 (33%)
		leucine-rich repeat	423..447	CDD:275381	13/52 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010