DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9003 and EBF1

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_565597.1	Gene:	EBF1 / 817087	AraportID:	AT2G25490	Length:	628	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	133/512 - (25%)
Similarity:	209/512 - (40%)	Gaps:	117/512 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 AVSINPKIMESSSDSCSLSSSTTPDVGLADQQRNMAGSAQDQSEDQSQTFLGATELDDELIKQLP 244
            |:..|||     ..|..||..:..||.....:|         |...:.|...|.|.....|..||
plant    18 AIYPNPK-----DASLLLSLGSFADVYFPPSKR---------SRVVAPTIFSAFEKKPVSIDVLP 68

  Fly   245 KEVLLRVFSYLD-VVSLCRCAQVCKYWNVLALDGSSWQKINLFDFQRDIEGPVIENISQRCRGFL 308
            .|.|..:|..|. ......||.|.|.|  |.|..|..||      :.|:...:.|: ...|.|.|
plant    69 DECLFEIFRRLSGPQERSACAFVSKQW--LTLVSSIRQK------EIDVPSKITED-GDDCEGCL 124

  Fly   309 -------KSLSLR---------GCQSVGDQSVRTLANHCHNIEHLDLSDCKKITDISTQSISRYC 357
                   |:..:|         |...:|..|:|.             |:..|::|:..:||.|.|
plant   125 SRSLDGKKATDVRLAAIAVGTAGRGGLGKLSIRG-------------SNSAKVSDLGLRSIGRSC 176

  Fly   358 SKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKFSSKGCKQ 422
            ..|.:::|.:.|.||||.|..:::||..|.::.::.|..|::.|:.|:|:.|..|.:.:.:.|.:
plant   177 PSLGSLSLWNVSTITDNGLLEIAEGCAQLEKLELNRCSTITDKGLVAIAKSCPNLTELTLEACSR 241

  Fly   423 INDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAAN--CH----KLQKLCVSKCA-------- 473
            |.|..::.:|:.|..|..:::.:|..:.|..|..|.:|  |.    |||.|.|:..:
plant   242 IGDEGLLAIARSCSKLKSVSIKNCPLVRDQGIASLLSNTTCSLAKLKLQMLNVTDVSLAVVGHYG 306

  Fly   474 -DLTDLTLLSLSQHNHL----------------LNTLEVSGCRNFTDIGFQALGRNCKYLERMDL 521
             .:|||.|..||   |:                ||:|.::.|:..||:|.:::|:.|..:::..:
plant   307 LSITDLVLAGLS---HVSEKGFWVMGNGVGLQKLNSLTITACQGVTDMGLESVGKGCPNMKKAII 368

  Fly   522 EECSQITDLTLAHLATGCPSLEKLTLSHCELITDDG----------------------IRHLTTG 564
            .:...::|..|...|....|||.|.|..|..:|..|                      ||.||||
plant   369 SKSPLLSDNGLVSFAKASLSLESLQLEECHRVTQFGFFGSLLNCGEKLKAFSLVNCLSIRDLTTG 433

  Fly   565 -----SCAAEILSVLELDNCPLITDRTLEHLVS-CHNLQRIELFDCQLITRTAIRKL 615
                 .|:|  |..|.:.|||...|..|..:.. |..|:.|:|...:.||.:....|
plant   434 LPASSHCSA--LRSLSIRNCPGFGDANLAAIGKLCPQLEDIDLCGLKGITESGFLHL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	17/45 (38%)
		leucine-rich repeat	280..307	CDD:275381	5/26 (19%)
		AMN1	<308..453	CDD:187754	40/160 (25%)
		leucine-rich repeat	308..327	CDD:275381	7/34 (21%)
		leucine-rich repeat	334..359	CDD:275381	7/24 (29%)
		leucine-rich repeat	360..385	CDD:275381	10/24 (42%)
		leucine-rich repeat	386..411	CDD:275381	7/24 (29%)
		AMN1	<409..586	CDD:187754	60/234 (26%)
		leucine-rich repeat	412..437	CDD:275381	6/24 (25%)
		leucine-rich repeat	438..463	CDD:275381	7/30 (23%)
		leucine-rich repeat	464..515	CDD:275381	20/75 (27%)
		leucine-rich repeat	516..541	CDD:275381	3/24 (13%)
		leucine-rich repeat	542..561	CDD:275381	9/40 (23%)
		leucine-rich repeat	571..595	CDD:275381	8/24 (33%)
		leucine-rich repeat	596..621	CDD:275381	6/20 (30%)
EBF1	NP_565597.1	F-box-like	64..101	CDD:372399	14/38 (37%)
		AMN1	<149..298	CDD:187754	45/161 (28%)
		leucine-rich repeat	179..204	CDD:275381	10/24 (42%)
		leucine-rich repeat	205..230	CDD:275381	7/24 (29%)
		leucine-rich repeat	231..256	CDD:275381	6/24 (25%)
		leucine-rich repeat	257..283	CDD:275381	6/25 (24%)
		leucine-rich repeat	284..308	CDD:275381	5/23 (22%)
		leucine-rich repeat	309..336	CDD:275381	7/29 (24%)
		leucine-rich repeat	337..362	CDD:275381	9/24 (38%)
		leucine-rich repeat	363..388	CDD:275381	3/24 (13%)
		leucine-rich repeat	416..442	CDD:275381	7/25 (28%)
		AMN1	440..611	CDD:187754	16/51 (31%)
		leucine-rich repeat	443..468	CDD:275381	8/24 (33%)
		leucine-rich repeat	469..492	CDD:275381	6/20 (30%)
		leucine-rich repeat	493..519	CDD:275381
		leucine-rich repeat	520..545	CDD:275381
		leucine-rich repeat	546..571	CDD:275381
		leucine-rich repeat	572..591	CDD:275381
		leucine-rich repeat	598..619	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1195
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010