Protein Alignment CG9003 and Skp2

DIOPT Version :10

• Sequence 1: NP_001097271.1
• Gene: CG9003 / 36244
• FlyBaseID: FBgn0033639
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 126/565 - (22%)
• Similarity: 225/565 - (39%)
• Gaps: 106/565 - (18%)

  Fly    33 SSNSGGAGGSIELLCP-----------------------------PSGSSSISGSASFSSNSGAS 68
            ||.......::|.|||                             ||..|:::..|......|..
  Fly     2 SSRKHRGSENMENLCPVTRKRSTNKNHVSVVGALVSTTKSSHYEHPSSPSALTFEALEEMGIGML 66

  Fly    69 GSSSQTHSTAVS------SATDRSNNNGNNHNPSLQLNGNGGSNTRQHSSGSN--------SRQH 119
             .|.::.|:|:|      |||...|:|......|:....:...:|::.|.||.        :.:.
  Fly    67 -DSEESSSSALSAIALAVSATSDDNSNETTPCASVSRMAHQLQHTQRLSLGSTGDITLDSPAVED 130

  Fly   120 SSSSSNSNSSN---ISPPPSSSSSSRSNNNNNNHSSNIISGFCSTIWRSATFGSATPVINPLPAV 181
            |.|.|..::..   ::....||..|..:.|:|:.|..:.:...:....:...|:|:  :|..|:.
  Fly   131 SLSMSRQSAEKLQILAQAKRSSLGSEGSGNSNSPSKRLRNPLAAVTCNNQIDGTAS--LNFQPST 193

  Fly   182 SINPKIMESSSDSCSLSSSTTPDVGLADQ---QRNMAGSAQDQSEDQSQTFLGATELDDELIKQL 243
            |...::.::...|   :::.|..:..||.   .|..|.||...|             .....::|
  Fly   194 SRLAQVRQAKKPS---TTNITTRIVAADSFFVFRTPAMSAHINS-------------GINYFERL 242

  Fly   244 PKEVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKINLFDFQRDIEGPVIENISQR----- 303
            ..|:||.:|.:|...:|.|.|.||:.:|..:.|.:.|.:::|  ..|.|....:|.|.:|
  Fly   243 SDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDL--GLRTIRPGALEQIVRRGVLVI 305

  Fly   304 ------------------CRGFLKSLSLRGCQSVGDQSVRTLANHCHNIEHLDLSDCKKITDIST 350
                              .|..|:.|.| ...|:...|:.||.:||..::.:.|.:.:...||..
  Fly   306 RLAQTSIQEPAFAPYTEVFRTRLQYLDL-SMASITRSSLLTLLSHCRQLKKISLENIELDDDICA 369

  Fly   351 QSISRYCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARG-CVKLRK 414
            :....  ..|.|:||...|.:|.||::.:.:...:|..:|:||..| |.:.|.||... ...|.:
  Fly   370 EIAKN--EALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDL-SADAVTALVTHISPNLIR 431

  Fly   415 FSSKGCKQI-NDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCADLTDL 478
            .:..||::: .|:.:..|.|.||.|:.|:|..|.::|.:.|..: .....|:.|.||:|..:...
  Fly   432 LNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAI-MKFKMLEYLSVSRCYLIPAT 495

  Fly   479 TLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEE 523
            ..:.|..... |..|::.|.  .:|...:.|.   |.|.:|.:.:
  Fly   496 KFIELKSMPS-LTYLDIFGM--LSDTAMEVLE---KQLPKMGINK 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box_FBXL2-like	237..281	CDD:438887	13/43 (30%)
		leucine-rich repeat	280..307	CDD:275381	8/49 (16%)
		AMN1	<308..453	CDD:187754	42/146 (29%)
		leucine-rich repeat	308..327	CDD:275381	5/18 (28%)
		leucine-rich repeat	334..359	CDD:275381	3/24 (13%)
		leucine-rich repeat	360..385	CDD:275381	8/24 (33%)
		leucine-rich repeat	386..411	CDD:275381	9/25 (36%)
		AMN1	<409..586	CDD:187754	28/116 (24%)
		leucine-rich repeat	412..437	CDD:275381	7/25 (28%)
		leucine-rich repeat	438..463	CDD:275381	6/24 (25%)
		leucine-rich repeat	464..515	CDD:275381	11/50 (22%)
		leucine-rich repeat	516..541	CDD:275381	2/8 (25%)
		leucine-rich repeat	542..561	CDD:275381
		leucine-rich repeat	571..595	CDD:275381
		leucine-rich repeat	596..621	CDD:275381
Skp2	NP_730815.2	F-box_DmSKP2-like	239..281	CDD:438920	14/41 (34%)
		leucine-rich repeat	302..327	CDD:275381	1/24 (4%)
		AMN1	309..480	CDD:187754	44/175 (25%)
		leucine-rich repeat	328..352	CDD:275381	9/24 (38%)
		leucine-rich repeat	353..376	CDD:275381	3/24 (13%)
		leucine-rich repeat	377..402	CDD:275381	8/24 (33%)
		leucine-rich repeat	403..428	CDD:275381	9/25 (36%)
		leucine-rich repeat	429..455	CDD:275381	7/25 (28%)
		leucine-rich repeat	456..480	CDD:275381	6/24 (25%)
		leucine-rich repeat	481..500	CDD:275381	5/18 (28%)
		leucine-rich repeat	506..529	CDD:275381	7/27 (26%)