Protein Alignment CG9003 and fbxl6

DIOPT Version :10

• Sequence 1: NP_001097271.1
• Gene: CG9003 / 36244
• FlyBaseID: FBgn0033639
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001296447.1
• Gene: fbxl6 / 323163
• ZFINID: ZDB-GENE-060810-162
• Length: 564
• Species: Danio rerio
• Alignment Length: 603
• Identity: 126/603 - (20%)
• Similarity: 214/603 - (35%)
• Gaps: 166/603 - (27%)

  Fly   111 SSGSNSRQHSSSSSNSNSSNISP-----PPSSSSSSRSNNNNN-------------NHS------ 151
            :..|::...::.||.:.:|...|     |....:.|..::.:.             |::
Zfish     6 AQASSAEMSAAQSSRAETSPTKPAKRKAPLKRKADSLKDDKSKKKKRKPVKRTVRPNYTVQEGED 70

  Fly   152 -----SNIISGFCSTIWRSATFGSATPVINPLPAVSINPKIMESSSDSCSLSSSTTPDVGLADQQ 211
                 |||.||  .::|:            |...|....|..:.:....|.|......|
Zfish    71 MLLIISNISSG--DSVWK------------PKRKVGKKKKTNKKAKTKGSTSKKEKAPV------ 115

  Fly   212 RNMAGSAQDQSEDQSQTFLGA-TELDDELIKQLPKEVLLRVFSYL-----DVVSLCRCAQVCKYW 270
            :......:::::|:......| |:..|...:.||.|:|:::|.:.     .|..|||..:||:.|
Zfish   116 KTEVLKVREETDDKHDVMDSAKTDRFDHWGQSLPLEILVKIFQFAVFQDGAVPLLCRVGRVCRLW 180

  Fly   271 NVLALDGSSWQKINLFDFQRDIEGPVIENISQRCRGFL-----KSLSLRGCQSVGDQSVRTLA-N 329
            |..|.....|:.:::                    |:.     || .|.|.:.....:|..|| |
Zfish   181 NGAASSPILWRSVSI--------------------GYCWIEPGKS-QLPGTEQKIKNTVDWLAEN 224

  Fly   330 HCHNIEHLDLSDCKKITDISTQSISRYCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWC 394
            ....:....|...||..|...|.:|:.|..|.::.|..|:.:|:.:.:.|...|.:|.:|||.
Zfish   225 RLFQLREFSLCHWKKNVDYVIQKVSQSCLSLHSLKLSYCTGMTEKAFQNLGADCQSLEDINVQ-- 287

  Fly   395 HLISENGVEALARGCVKLRKFSSKGCKQI-------NDNAIMCLAK-YCPDLMVLNLHSCETITD 451
            |  ||..|:    |.|...:......|:|       :|..:..|:| .||:|.:|.::   |..|
Zfish   288 H--SEINVD----GLVSFLEAYGNQIKKIYFTHSTKSDKLLSALSKGCCPELRLLEIN---TKLD 343

  Fly   452 SSIRQLAANCHKLQKLCVS----KCADLTDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRN 512
            ....||        .:|:.    .|..|....|::::....::..:..|.|      ||..|...
Zfish   344 GGYSQL--------PICIQGLQIGCPKLQTFRLMNVTAVPKMIRNIPSSTC------GFPMLEEL 394

  Fly   513 CKYLERMDLEECSQITDLTLAHLATGCPSLEKLTLSHCELITDDGIRHLTTGSCA---------- 567
            |     :.....|.:||..|.::..|.|:|..|.|.....||..|:..|   .|.
Zfish   395 C-----IATSFHSFMTDNDLNNVLHGSPNLRVLDLRGGSRITPTGLYAL---PCERLECFYWGLY 451

  Fly   568 --------------------AEILSVLELDNCPLITDRTLE-------HLVSCHNLQRIELFDCQ 605
                                :..|..|:|.|.| .::..||       |.|.....:.:.|...:
Zfish   452 FNSNTMVASKKGIHMLAQKWSNTLRELDLANQP-FSEEDLEIAMGHLAHSVGVEFFRSLNLSGTK 515

  Fly   606 LITRTAIRKLKNHLPNIK 623
             ||.:|:|.|.|..|.:|
Zfish   516 -ITSSALRLLINQAPALK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box_FBXL2-like	237..281	CDD:438887	15/48 (31%)
		leucine-rich repeat	280..307	CDD:275381	1/26 (4%)
		AMN1	<308..453	CDD:187754	42/158 (27%)
		leucine-rich repeat	308..327	CDD:275381	5/23 (22%)
		leucine-rich repeat	334..359	CDD:275381	7/24 (29%)
		leucine-rich repeat	360..385	CDD:275381	6/24 (25%)
		leucine-rich repeat	386..411	CDD:275381	9/24 (38%)
		AMN1	<409..586	CDD:187754	43/218 (20%)
		leucine-rich repeat	412..437	CDD:275381	6/32 (19%)
		leucine-rich repeat	438..463	CDD:275381	6/24 (25%)
		leucine-rich repeat	464..515	CDD:275381	10/54 (19%)
		leucine-rich repeat	516..541	CDD:275381	5/24 (21%)
		leucine-rich repeat	542..561	CDD:275381	6/18 (33%)
		leucine-rich repeat	571..595	CDD:275381	9/30 (30%)
		leucine-rich repeat	596..621	CDD:275381	7/24 (29%)
fbxl6	NP_001296447.1	F-box_FBXL6	145..191	CDD:438891	14/45 (31%)
		AMN1	213..396	CDD:187754	50/212 (24%)
		leucine-rich repeat	229..254	CDD:275381	7/24 (29%)
		leucine-rich repeat	255..280	CDD:275381	6/24 (25%)
		leucine-rich repeat	281..306	CDD:275381	10/32 (31%)
		leucine-rich repeat	307..334	CDD:275381	7/26 (27%)
		leucine-rich repeat	335..362	CDD:275381	7/37 (19%)
		AMN1	<391..>542	CDD:187754	34/152 (22%)
		leucine-rich repeat	391..418	CDD:275381	7/31 (23%)
		leucine-rich repeat	419..438	CDD:275381	6/18 (33%)
		leucine-rich repeat	445..473	CDD:275381	0/27 (0%)
		leucine-rich repeat	475..505	CDD:275381	9/30 (30%)
		leucine-rich repeat	506..530	CDD:275381	7/24 (29%)