DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9003 and Fbxl15

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001101073.1	Gene:	Fbxl15 / 309453	RGDID:	1306444	Length:	300	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	57/179 - (31%)
Similarity:	93/179 - (51%)	Gaps:	4/179 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 LMEINVSWCH--LISENGVEALARGCVKLRKFSSKGCKQINDNAIMCLAKYCPDLMVLNLHSCET 448
            |.|:.::.||  |:.|:.|..|||. .:||..:..||.|::..|:..||:.||.|..::|..|:.
  Rat    89 LQELALAPCHEWLLDEDLVPVLARN-PQLRSVALAGCGQLSRRALGALAEGCPRLQRISLAHCDW 152

  Fly   449 ITDSSIRQLAANCHKLQKLCVSKCADLTDLTLLSLSQHNHL-LNTLEVSGCRNFTDIGFQALGRN 512
            :...::|.||..|..|::|.::.|..|.|..::.|:|.... |.:|.::...|..|...|.|.||
  Rat   153 VDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARN 217

  Fly   513 CKYLERMDLEECSQITDLTLAHLATGCPSLEKLTLSHCELITDDGIRHL 561
            |..||.:||..|.::....:..||..||:|..|.:.||..:.:..:..|
  Rat   218 CPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRL 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689
		leucine-rich repeat	280..307	CDD:275381
		AMN1	<308..453	CDD:187754	23/68 (34%)
		leucine-rich repeat	308..327	CDD:275381
		leucine-rich repeat	334..359	CDD:275381
		leucine-rich repeat	360..385	CDD:275381
		leucine-rich repeat	386..411	CDD:275381	10/26 (38%)
		AMN1	<409..586	CDD:187754	47/154 (31%)
		leucine-rich repeat	412..437	CDD:275381	9/24 (38%)
		leucine-rich repeat	438..463	CDD:275381	7/24 (29%)
		leucine-rich repeat	464..515	CDD:275381	16/51 (31%)
		leucine-rich repeat	516..541	CDD:275381	8/24 (33%)
		leucine-rich repeat	542..561	CDD:275381	4/18 (22%)
		leucine-rich repeat	571..595	CDD:275381
		leucine-rich repeat	596..621	CDD:275381
Fbxl15	NP_001101073.1	F-box	18..55	CDD:395521
		leucine-rich repeat	62..88	CDD:275381
		leucine-rich repeat	89..115	CDD:275381	10/26 (38%)
		Interaction with SMURF1. /evidence=ECO:0000250	113..269		47/155 (30%)
		leucine-rich repeat	116..141	CDD:275381	9/24 (38%)
		AMN1	<139..>268	CDD:187754	39/128 (30%)
		leucine-rich repeat	142..167	CDD:275381	7/24 (29%)
		leucine-rich repeat	168..194	CDD:275381	7/25 (28%)
		leucine-rich repeat	195..220	CDD:275381	9/24 (38%)
		leucine-rich repeat	221..245	CDD:275381	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346624
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940