Protein Alignment CG9003 and Fbxl5

DIOPT Version :10

• Sequence 1: NP_001097271.1
• Gene: CG9003 / 36244
• FlyBaseID: FBgn0033639
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001388361.1
• Gene: Fbxl5 / 305424
• RGDID: 1306887
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 125/561 - (22%)
• Similarity: 190/561 - (33%)
• Gaps: 208/561 - (37%)

  Fly   183 INPKIMESSSDSCSLSSSTTPDVGLA------DQQRNMAGSAQDQSEDQSQTFLGATELDDELIK 241
            |..|::   :..||...:.....||:      ::|:....|..::|:.:::....:|.     |.
  Rat   150 IKKKVI---AQHCSQKDTAELLRGLSLWNQAEERQKVFKYSVDEKSDAEAEVSEHSTG-----IT 206

  Fly   242 QLPKEVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKINLFDFQRD--IEGPVIE------ 298
            .||.||:|.:||||:...||||:||...|:.||..||.|:.:....:.|.  ..||..|
  Rat   207 HLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHLYPVHWARGDWYSGPATELDTEPD 271

  Fly   299 ------------------------------------NISQRCRGFL---------------KSLS 312
                                                :|:|..:..|               |:|.
  Rat   272 EEWVRSRKDESRAFQEWDEDADIDESEESAEESVAISIAQMEKRLLHGLIHNVLPYVGTSVKTLV 336

  Fly   313 LRGCQSVGDQSVRTLANHCHNIE---------------------------HLDLSDCKKITDIST 350
            |....:|..:.||.:...|.|:|                           |||||.|:||||::.
  Rat   337 LAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDMAL 401

  Fly   351 QSISRYCSKLTAIN------------------------------LHSCSN--------------- 370
            :.|||....||:..                              ||:.:|
  Rat   402 EKISRALGVLTSHQSGVLKSAGKTTSTPWTNKDITMPSTTQYACLHNLTNKGVGEEIDSEHTWTE 466

  Fly   371 -ITDNSLK----YLSDGCPNLMEIN--VSWCHLISENGVEALA-------RGCVKLRKFSSKGCK 421
             ::..|..    ::.| ..:|.:|.  |.|.|    ..||:|.       .||      ||.||.
  Rat   467 PVSSESFTPPYVWMLD-AEDLADIEDAVEWRH----RNVESLCVMETASNFGC------SSSGCY 520

  Fly   422 Q---INDNAIMCLAKYC--PDLMVLNLHSCET----ITDSSIRQLAANCHKLQKLCVSKCADL-- 475
            .   :.....:|..::|  |.........|.|    .|.|::...:|.|.|..:..:.:..||
  Rat   521 SKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMSALPAASAVCRKALRTTLPRGKDLIY 585

  Fly   476 ---------TDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQ--ALGRNCKYLERMDLEECSQITD 529
                     |...||.||          :|||...||.|.:  .||....|||.::|..|..:|.
  Rat   586 FGSEKSDQETGRVLLFLS----------LSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTVTG 640

  Fly   530 LTLAHLATGCPSLEKLTLSHCELI------TDDGIRHLTTG 564
            ..|..|.:.||||......:|:.|      |..|.::|..|
  Rat   641 AGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQCG 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box_FBXL2-like	237..281	CDD:438887	21/43 (49%)
		leucine-rich repeat	280..307	CDD:275381	7/70 (10%)
		AMN1	<308..453	CDD:187754	50/254 (20%)
		leucine-rich repeat	308..327	CDD:275381	7/33 (21%)
		leucine-rich repeat	334..359	CDD:275381	14/51 (27%)
		leucine-rich repeat	360..385	CDD:275381	7/74 (9%)
		leucine-rich repeat	386..411	CDD:275381	10/33 (30%)
		AMN1	<409..586	CDD:187754	48/184 (26%)
		leucine-rich repeat	412..437	CDD:275381	6/29 (21%)
		leucine-rich repeat	438..463	CDD:275381	6/28 (21%)
		leucine-rich repeat	464..515	CDD:275381	15/63 (24%)
		leucine-rich repeat	516..541	CDD:275381	8/24 (33%)
		leucine-rich repeat	542..561	CDD:275381	5/24 (21%)
		leucine-rich repeat	571..595	CDD:275381
		leucine-rich repeat	596..621	CDD:275381
Fbxl5	NP_001388361.1	Hr_FBXL5	7..160	CDD:213984	2/12 (17%)
		F-box_FBXL5	205..245	CDD:438890	21/39 (54%)
		leucine-rich repeat	332..345	CDD:275381	4/12 (33%)
		AMN1	<340..>404	CDD:187754	16/63 (25%)
		leucine-rich repeat	358..384	CDD:275381	1/25 (4%)
		leucine-rich repeat	385..448	CDD:275381	16/62 (26%)
		leucine-rich repeat	449..516	CDD:275381	13/77 (17%)
		leucine-rich repeat	540..571	CDD:275381	7/30 (23%)
		leucine-rich repeat	573..626	CDD:275381	15/62 (24%)
		AMN1	<602..>653	CDD:187754	20/60 (33%)
		leucine-rich repeat	627..652	CDD:275381	8/24 (33%)