DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9003 and Amn1

DIOPT Version :9

Sequence 1:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001106895.1	Gene:	Amn1 / 232566	MGIID:	2442933	Length:	258	Species:	Mus musculus

Alignment Length:	258	Identity:	77/258 - (29%)
Similarity:	132/258 - (51%)	Gaps:	35/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 SISRYCSKLTAINLHSCSNITDNSLKYLS-DGCPNLMEINVSWCHLISENGVEALARGCVKLRKF 415
            :||||.|.:..:.    |||.|..:|.:| .|  .:.:.|:|          |.|.   .::::.
Mouse    21 NISRYISDIKYLP----SNIKDRLIKIMSIRG--RITDSNIS----------EVLH---PEVQRL 66

  Fly   416 SSKGCKQINDNAIMCLAKYCPDLMVLNLHSC----ETITDSSIRQLAANCHKLQKLCVSKCADLT 476
            ..:.| .|:|.|:..|.| |..|..|||.||    .:||...|:.:|::|..|.::.:..|..:|
Mouse    67 DLRSC-DISDVALQHLCK-CRKLKALNLKSCREHRNSITSEGIKAVASSCSDLHEIYLKGCCSVT 129

  Fly   477 DLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLTLAHLATG--C 539
            |..:|:|:.:.|||..:::.||...||:...|||:||.:|:.:|: ..:|::|..:..|.:|  .
Mouse   130 DEGVLALALNCHLLKIIDLGGCLGITDVSLHALGKNCPFLQCVDI-STTQVSDNGVVALVSGPCA 193

  Fly   540 PSLEKLTLSHCELITDDGIRHLTTGSCAAEILSVLELDNCPLITDRT---LEHLVSCHNLQRI 599
            ..||::.:.:|..:||..:....|   |...:.:|....|||||||:   ||.|:....|:::
Mouse   194 KQLEEINMRYCINLTDKAVEAALT---ACPRICILLFHGCPLITDRSQEVLEQLIGSRKLKQV 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689
		leucine-rich repeat	280..307	CDD:275381
		AMN1	<308..453	CDD:187754	31/105 (30%)
		leucine-rich repeat	308..327	CDD:275381
		leucine-rich repeat	334..359	CDD:275381	4/6 (67%)
		leucine-rich repeat	360..385	CDD:275381	7/25 (28%)
		leucine-rich repeat	386..411	CDD:275381	4/24 (17%)
		AMN1	<409..586	CDD:187754	56/182 (31%)
		leucine-rich repeat	412..437	CDD:275381	7/24 (29%)
		leucine-rich repeat	438..463	CDD:275381	11/28 (39%)
		leucine-rich repeat	464..515	CDD:275381	18/50 (36%)
		leucine-rich repeat	516..541	CDD:275381	6/26 (23%)
		leucine-rich repeat	542..561	CDD:275381	5/18 (28%)
		leucine-rich repeat	571..595	CDD:275381	11/26 (42%)
		leucine-rich repeat	596..621	CDD:275381	1/4 (25%)
Amn1	NP_001106895.1	leucine-rich repeat	15..38	CDD:275381	8/20 (40%)
		AMN1	37..257	CDD:187754	69/238 (29%)
		leucine-rich repeat	63..86	CDD:275381	7/24 (29%)
		leucine-rich repeat	87..116	CDD:275381	11/28 (39%)
		leucine-rich repeat	117..142	CDD:275381	6/24 (25%)
		leucine-rich repeat	143..168	CDD:275381	10/24 (42%)
		leucine-rich repeat	169..195	CDD:275381	6/26 (23%)
		leucine-rich repeat	196..221	CDD:275381	7/27 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920