DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9003 and AMN1

DIOPT Version :9

Sequence 1:NP_001097271.1 Gene:CG9003 / 36244 FlyBaseID:FBgn0033639 Length:651 Species:Drosophila melanogaster
Sequence 2:NP_001106873.1 Gene:AMN1 / 196394 HGNCID:27281 Length:258 Species:Homo sapiens


Alignment Length:260 Identity:73/260 - (28%)
Similarity:133/260 - (51%) Gaps:37/260 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   351 QSISRYCSKLTAINLHSCSNITDNSLKYLS-DGCPNLMEINVSWCHLISENGVEAL-ARGCVKLR 413
            ::||||.:.:..:.    .||.|..:|.:| .|  .:.:.|:|   .|....|:.| .|.|    
Human    20 KNISRYLTDIKPLP----PNIKDRLIKIMSMQG--QITDSNIS---EILHPEVQTLDLRSC---- 71

  Fly   414 KFSSKGCKQINDNAIMCLAKYCPDLMVLNLHSCE----TITDSSIRQLAANCHKLQKLCVSKCAD 474
                    .|:|.|::.|:. |..|..|||::.:    ::|...|:.:|::|..|.:..:.:|.:
Human    72 --------DISDAALLHLSN-CRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCN 127

  Fly   475 LTDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLTLAHLATG- 538
            |||..:::|:.:..||..:::.||.:.||:...|||:||.:|:.:|. ..:|::|..:..|.:| 
Human   128 LTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDF-SATQVSDSGVIALVSGP 191

  Fly   539 -CPSLEKLTLSHCELITDDGIRHLTTGSCAAEILSVLELDNCPLITDRT---LEHLVSCHNLQRI 599
             ...||::.:.||..:||..:..:.| .|..  :.:|....||||||.:   ||.||..:.|:::
Human   192 CAKKLEEIHMGHCVNLTDGAVEAVLT-YCPQ--IRILLFHGCPLITDHSREVLEQLVGPNKLKQV 253

  Fly   600  599
            Human   254  253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9003NP_001097271.1 F-box-like 240..285 CDD:289689
leucine-rich repeat 280..307 CDD:275381
AMN1 <308..453 CDD:187754 27/107 (25%)
leucine-rich repeat 308..327 CDD:275381
leucine-rich repeat 334..359 CDD:275381 4/7 (57%)
leucine-rich repeat 360..385 CDD:275381 6/25 (24%)
leucine-rich repeat 386..411 CDD:275381 7/25 (28%)
AMN1 <409..586 CDD:187754 52/182 (29%)
leucine-rich repeat 412..437 CDD:275381 5/24 (21%)
leucine-rich repeat 438..463 CDD:275381 8/28 (29%)
leucine-rich repeat 464..515 CDD:275381 17/50 (34%)
leucine-rich repeat 516..541 CDD:275381 6/26 (23%)
leucine-rich repeat 542..561 CDD:275381 6/18 (33%)
leucine-rich repeat 571..595 CDD:275381 11/26 (42%)
leucine-rich repeat 596..621 CDD:275381 1/4 (25%)
AMN1NP_001106873.1 AMN1 37..257 CDD:187754 67/239 (28%)
leucine-rich repeat 63..86 CDD:275381 9/35 (26%)
leucine-rich repeat 87..116 CDD:275381 8/28 (29%)
leucine-rich repeat 117..142 CDD:275381 6/24 (25%)
leucine-rich repeat 143..168 CDD:275381 10/24 (42%)
leucine-rich repeat 169..195 CDD:275381 6/26 (23%)
leucine-rich repeat 196..221 CDD:275381 8/25 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1046098at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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