Protein Alignment CG9003 and EEED8.10

DIOPT Version :9

• Sequence 1: NP_001097271.1
• Gene: CG9003 / 36244
• FlyBaseID: FBgn0033639
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001040757.1
• Gene: EEED8.10 / 173919
• WormBaseID: WBGene00017138
• Length: 738
• Species: Caenorhabditis elegans
• Alignment Length: 677
• Identity: 133/677 - (19%)
• Similarity: 242/677 - (35%)
• Gaps: 192/677 - (28%)

  Fly    60 SFSSNSGASGSSSQTHSTAVSSATDRSNNNGNNHNPSLQLNG---------NGGSNTRQHSSGSN 115
            ||:||.|::||:....|  :..|..|.      |..:|:..|         :..:..|..|.|..
 Worm     6 SFTSNLGSAGSAKSQQS--MFKALRRL------HGQNLESRGLHDMTEAFQSFVTRARFFSIGKL 62

  Fly   116 SRQHSSSS--------------SNSNSSNISPPPSSSSSSRSNNNNNNHSSNIISGFCSTIWRS- 165
            .|..|.|:              ::.::.:........:|....:.:.:....::|...:.:.:|
 Worm    63 RRTWSHSAAEFMKYRRLLPMLLADGDAFDGGETDDFDASIAFQHTSRDDRKIVVSNISAKVTQSQ 127

  Fly   166 -----ATFGSATPVINP-----------LPAVSIN---PKIMESSSDSCSLSSSTTP-------- 203
                 :.:|..|..|.|           ||..|.|   ..|....|:....:.:..|
 Worm   128 LQSFFSQYGKITSCILPREEKKTSVFGTLPKHSRNCGTATITFKKSEHADRAKNANPEELKFYDQ 192

  Fly   204 ---------------------DVG-LADQQRNMAGSAQDQSEDQSQTF-LGATELDDELIKQLPK 245
                                 ||| ..|...:.|.|.|..:....|:| ||          .:|.
 Worm   193 VMVVSAYVSKKRGGKGLVLSDDVGSREDTPLSRASSTQSLASGSEQSFNLG----------NVPD 247

  Fly   246 EVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKIN--------LFDFQRDIEGPVIENISQ 302
            ::|.||.|:|.:....|..:|.|.:...::  .||:.:|        :|:.||.:....::.|..
 Worm   248 KILRRVISFLPIHETIRLERVNKKFMEESI--KSWELVNKIALARETVFNKQRPMRTSHLKAILT 310

  Fly   303 RCRGFLKSLSLRGCQSVGDQSVRTLANHCHNIEHLDLSDCKKITDISTQSISRYCSKLTAINLHS 367
            |....|:||.:.|                  |.|| |.|.:
 Worm   311 RAGAHLRSLDVSG------------------IVHL-LDDRR------------------------ 332

  Fly   368 CSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKFSSKGCKQINDNAIMCLA 432
                   :||.::..||||:::::|..|..:| .:|.|......|.:.|.:|.:...|.|...|.
 Worm   333 -------ALKVIATCCPNLVDLDISGTHAQAE-ALEELGESLSHLEQLSYRGMETTGDKAFYFLL 389

  Fly   433 KYC------------------------PDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCA 473
            |.|                        ..|..|.|.....:.:.:...|..:|..|::|.:::|.
 Worm   390 KNCGHSLKFVDLRNSKRLHGRSFKLFGSQLESLYLDGSSKVDEMAFEDLCTSCGGLKELRINECY 454

  Fly   474 DLTD--LTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLTLAHLA 536
            .:||  |::::....:..:.||...|.::.|..|...:. :.:.:..:.|:..:.:.|..|..::
 Worm   455 KITDENLSMIARRMEDLSILTLCGDGFKSLTSAGLIHIS-HMRNITELALDYNALVNDELLISIS 518

  Fly   537 TGCPSLEKLTLSHC---ELITDDGIRHLTTGSCAAEILSVLELDNCPL--ITDRTLEHLVSCHNL 596
            .|.|.|..|:|::.   ..||.:|:      |....:..:.:||...|  :..:.||.|.|...|
 Worm   519 AGLPLLSSLSLANAGNDSSITAEGV------SAIKNLKELTQLDASSLAAVNSKVLEQLGSLKKL 577

  Fly   597 QRIELFDCQLITRTAIRKLKNHLPNIK 623
            :.|:|.:|..:....:| .|..:|||:
 Worm   578 EIIQLRNCTYLGDDGVR-AKLRMPNIR 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	12/52 (23%)
		leucine-rich repeat	280..307	CDD:275381	7/34 (21%)
		AMN1	<308..453	CDD:187754	31/168 (18%)
		leucine-rich repeat	308..327	CDD:275381	4/18 (22%)
		leucine-rich repeat	334..359	CDD:275381	5/24 (21%)
		leucine-rich repeat	360..385	CDD:275381	3/24 (13%)
		leucine-rich repeat	386..411	CDD:275381	6/24 (25%)
		AMN1	<409..586	CDD:187754	39/207 (19%)
		leucine-rich repeat	412..437	CDD:275381	8/48 (17%)
		leucine-rich repeat	438..463	CDD:275381	5/24 (21%)
		leucine-rich repeat	464..515	CDD:275381	11/52 (21%)
		leucine-rich repeat	516..541	CDD:275381	4/24 (17%)
		leucine-rich repeat	542..561	CDD:275381	6/21 (29%)
		leucine-rich repeat	571..595	CDD:275381	7/25 (28%)
		leucine-rich repeat	596..621	CDD:275381	6/24 (25%)
EEED8.10	NP_001040757.1	RRM	<101..273	CDD:223796	34/181 (19%)
		RRM_SF	114..197	CDD:240668	13/82 (16%)
		AMN1	<313..>464	CDD:187754	39/201 (19%)
		leucine-rich repeat	316..337	CDD:275381	11/70 (16%)
		leucine-rich repeat	344..368	CDD:275381	6/24 (25%)
		leucine-rich repeat	369..395	CDD:275381	8/25 (32%)
		AMN1	394..615	CDD:187754	44/218 (20%)
		leucine-rich repeat	396..418	CDD:275381	0/21 (0%)
		leucine-rich repeat	419..444	CDD:275381	5/24 (21%)
		leucine-rich repeat	445..470	CDD:275381	6/24 (25%)
		leucine-rich repeat	471..497	CDD:275381	5/26 (19%)
		leucine-rich repeat	498..520	CDD:275381	3/21 (14%)
		leucine-rich repeat	524..551	CDD:275381	7/32 (22%)
		leucine-rich repeat	552..576	CDD:275381	7/23 (30%)
		leucine-rich repeat	577..601	CDD:275381	6/24 (25%)
		leucine-rich repeat	602..627	CDD:275381	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.802101	Normalized mean entropy	S1900
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860