Protein Alignment CG9005 and FAM214B

DIOPT Version :9

• Sequence 1: NP_001369081.1
• Gene: CG9005 / 36243
• FlyBaseID: FBgn0033638
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_001304920.1
• Gene: FAM214B / 80256
• HGNCID: 25666
• Length: 538
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 161/574 - (28%)
• Similarity: 222/574 - (38%)
• Gaps: 139/574 - (24%)

  Fly   771 PGVLDQVSCRNADLNGGQNNNLLK-ATPATSGCQVCKRQKTQHNFANGKVHQPT-------NGKQ 827
            |||. |||..:......:.:..|| ..|:|.|.:..||.............:|:       .|..
Human    45 PGVY-QVSIFSPPAGTSEPHRALKRQAPSTEGPRELKRGPGLGAREGLPPEEPSTVGLLGPEGPG 108

  Fly   828 ASNGYASMHLE------AEKQPDVVQ-----ILATKLTPNIERCSLNPVERCKTPPPGVADHIVV 881
            ...|.||.|..      .|::..|..     ..:....|:...|:........:|.||
Human   109 LGLGVASQHFSHRGLCVVEQRSSVTSSWTSGAWSPPCPPSNASCNTLHTRDWASPDPG------- 166

  Fly   882 QFKTPLSQVPAKHQPDAMVPLQQ--QQLGKSSSKPAQLRLNCGSNLLESETP------------- 931
             .:..|.:.|....|..:..|..  ..|.:...|.....:..|.:|...|:|
Human   167 -GQGSLGESPGPAPPGQLHTLDTDLHSLAQIGGKSPVAGVGNGGSLWPRESPGTANGHSPEHTPP 230

  Fly   932 ---PPMTSPQMRKALPKVNLTTIFCSSAPIAIGCPAFSFDPAALSHARSQLLAPDVSVT---PPV 990
               ||...|..|:.||...                                 |||||..   |..
Human   231 GPGPPGPCPTKRRLLPAGE---------------------------------APDVSSEEEGPAP 262

  Fly   991 QK---SFSAPTLPHAASLSVSPRFSKQALAAHKRRSRHLSDRSDRSSLG----SDEQLSDEDLES 1048
            ::   |...||..:::....:| |....|...|   ..:.|.:|...:|    ...:|....|.|
Human   263 RRRRGSLGHPTAANSSDAKATP-FWSHLLPGPK---EPVLDPTDCGPMGRRLKGARRLKLSPLRS 323

  Fly  1049 -----GLCSPAGGSPLKCRARLAAQFGGRPLLGNLEESLLQRRLMPKIEVMGFTLQLGASGGFCP 1108
                 ||.||...||:...|      ..|.||||.|||||:.|..|...:.|||.::||||.:||
Human   324 LRKGPGLLSPPSASPVPTPA------VSRTLLGNFEESLLRGRFAPSGHIEGFTAEIGASGSYCP 382

  Fly  1109 TQVNIPAVSYFYELHGETLSTPYLCEI---RLPRKGYSVPRSGTVQATLLNPIGTVVRMFVIPYD 1170
            ..|.:|....|:::..:....|:|..:   .|.|||||||:.||||.||.||..|||:||::.:|
Human   383 QHVTLPVTVTFFDVSEQNAPAPFLGIVDLNPLGRKGYSVPKVGTVQVTLFNPNQTVVKMFLVTFD 447

  Fly  1171 MRDMPPLHRTFIRQRILAEELSQDQDEGHKVPRSPTVTSTTSKLGHFISAEQMKRLRYSIHLKFQ 1235
            ..|||..|.||:|.|:....:.   :||:..|        |.:|           |.|.:||:|:
Human   448 FSDMPAAHMTFLRHRLFLVPVG---EEGNANP--------THRL-----------LCYLLHLRFR 490

  Fly  1236 TSRSGRLCLHTDIRLLISRRT-DCDTAAAHAKGVLEAPNELVTDTMMPAEPRYS 1288
            :||||||.||.|||||.|||: :.||.         .|.||...|..|..||||
Human   491 SSRSGRLSLHGDIRLLFSRRSLELDTG---------LPYELQAVTEAPHNPRYS 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9005	NP_001369081.1	DUF4210	1074..1131	CDD:404751	23/56 (41%)
		Chromosome_seg	1226..1290	CDD:404729	32/64 (50%)
FAM214B	NP_001304920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		16/69 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..300		34/211 (16%)
		DUF4210	348..402	CDD:316437	23/53 (43%)
		Chromosome_seg	480..536	CDD:316412	33/76 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	71	1.000	Domainoid score	I9456
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002608
OrthoInspector	1	1.000	-	-		otm41591
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13199
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1702
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.040