Protein Alignment atos and Atosb

DIOPT Version :10

• Sequence 1: NP_001369081.1
• Gene: atos / 36243
• FlyBaseID: FBgn0033638
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_766279.1
• Gene: Atosb / 230088
• MGIID: 2441854
• Length: 538
• Species: Mus musculus
• Alignment Length: 782
• Identity: 199/782 - (25%)
• Similarity: 272/782 - (34%)
• Gaps: 263/782 - (33%)

  Fly   521 HVE-PLPPSPAPRSLRPCGGDPASTPTGGGGLHAATPTGLGARTSALTPTTTAGGSNCDNGKPGM 584
            ||: .|.||..|.:      .|:..|...|.|......|.          :.|||:.    .||:
Mouse     3 HVQAELSPSSEPEA------GPSQPPVRQGTLQGGLLMGY----------SPAGGAT----SPGV 47

  Fly   585 GQILDELDGDTSLSHRERQLQKYRKRMQRRDKKRERKATPDRLNSRQQSEEPMDEGEESQTQSQT 649
            .|: .........|...|.|   ::.....:..||.|..|. |.:|:
Mouse    48 YQV-SIFSPSAGASEPPRAL---KRPAPPTEGPRELKRGPG-LGARE------------------ 89

  Fly   650 TSETQSLALTLQQPRRIAMIS-TGTQTSLSSCQQCGSEKTLLCLSCTGGGGAHGGSNGTANGSTN 713
                   .|..::|..:.::| .|....|....|..|...|..:.       |||:  |.:..|:
Mouse    90 -------GLPPEEPSTVGLLSPEGLGLGLGVASQHFSHHGLCVVE-------HGGN--TTSPWTS 138

  Fly   714 GATDDGDDSDTTASEMEETSSCSLSSADLIVGTPRNNAELLLQAIQRTPKNRNRKPHPGVLDQVS 778
            |       :.:|.......|..:|.:.|.  ..|....:..|          ...|.|....|:.
Mouse   139 G-------TQSTPWLSSNASFNTLHTRDW--AFPDQGGQGCL----------GETPGPAPSGQLH 184

  Fly   779 CRNADLN-----GGQNNNLLKATPATSGCQVCKRQKTQHNFANGKVHQPTNGKQASNGYASMHLE 838
            ..:.||:     ||      |:..|..|              ||....|......:||::..|
Mouse   185 TLDTDLHNLAQIGG------KSPVARVG--------------NGSNPWPRESHGTANGHSPEH-- 227

  Fly   839 AEKQPDVVQILATKLTPNIERCSLNPVERCKTPP-PGVADHIVVQFKTPLSQVPAKHQPDAMVPL 902
                                           ||| ||                     |....|.
Mouse   228 -------------------------------TPPGPG---------------------PPGPCPT 240

  Fly   903 QQQQLGKSSSKPAQLRLNCGSNLLESETPPPMTSPQMRKALPKVNLTTIFCSSAPIAIGCPAFSF 967
            :::.|      ||...|:..|   |.|.|    :|:.|:.                .:|||.
Mouse   241 KRRLL------PAGETLDVSS---EDEGP----APRRRRG----------------TLGCPL--- 273

  Fly   968 DPAALSHARSQLLAPDVSVTPPVQKSFSAPTLPHAASLSVSP--RFSKQALAAHKRRSRHLSDRS 1030
              ||.|        .|...||........|..|.......||  |..|.|     ||.:..|.|:
Mouse   274 --AANS--------SDAKATPFWSHLLPGPKEPVLDPTDCSPMGRRLKGA-----RRLKLSSLRT 323

  Fly  1031 DRSSLGSDEQLSDEDLESGLCSPAGGSPLKCRARLAAQFGGRPLLGNLEESLLQRRLMPKIEVMG 1095
            .|..             .||.||...||....|      ..|.||||.|||||:.|..|...:.|
Mouse   324 LRKG-------------PGLLSPPSASPFPTPA------VSRTLLGNFEESLLRGRFAPSGHIEG 369

  Fly  1096 FTLQLGASGGFCPTQVNIPAVSYFYELHGETLSTPYLCEIRLP---RKGYSVPRSGTVQATLLNP 1157
            ||.::||||.:||..|.:|....|:::..:....|:|..:.|.   |||||||:.||:|.||.||
Mouse   370 FTAEIGASGSYCPQHVTLPVTVTFFDVSEQNAPAPFLGVVDLTPLGRKGYSVPKVGTIQVTLFNP 434

  Fly  1158 IGTVVRMFVIPYDMRDMPPLHRTFIRQRILAEELSQDQDEGHKVPRSPTVTSTTSKLGHFISAEQ 1222
            ..|||:||::.:|..|||..|.||:|.|:....:.   :||:..|        |.:|
Mouse   435 NQTVVKMFLVTFDFSDMPAAHMTFLRHRLFLVPVG---EEGNASP--------THRL-------- 480

  Fly  1223 MKRLRYSIHLKFQTSRSGRLCLHTDIRLLISRRT-DCDTAAAHAKGVLEAPNELVTDTMMPAEPR 1286
               |.|.:||:|::||||||.||.|||||.|||: :.||.         .|.||...|..|..||
Mouse   481 ---LCYLLHLRFRSSRSGRLSLHGDIRLLFSRRSLELDTG---------LPYELQAVTEAPHNPR 533

  Fly  1287 YS 1288
            ||
Mouse   534 YS 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atos	NP_001369081.1	DUF4210	1074..1131	CDD:404751	23/56 (41%)
		Chromosome_seg	1226..1290	CDD:464021	32/64 (50%)
Atosb	NP_766279.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..99		28/145 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..185		4/29 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	199..270		26/167 (16%)
		Required for macropage invasion. /evidence=ECO:0000269|PubMed:35319107	348..430		36/81 (44%)
		DUF4210	348..405	CDD:404751	23/56 (41%)
		Transactivation domain 1 (TAD1). /evidence=ECO:0000269|PubMed:35319107	436..444		5/7 (71%)
		Chromosome_seg	480..537	CDD:464021	33/76 (43%)