Protein Alignment Egm and Acox2

DIOPT Version :9

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001155139.1
• Gene: Acox2 / 93732
• MGIID: 1934852
• Length: 681
• Species: Mus musculus
• Alignment Length: 600
• Identity: 121/600 - (20%)
• Similarity: 189/600 - (31%)
• Gaps: 211/600 - (35%)

  Fly   118 SPETLRQLGLYGLN--VSTDYEGKGYGWSASLMASEPDST-----------------------DI 157
            |.|.:.:.|..|.|  :.|.|.....|....|...|.::|                       |:
Mouse   131 SDEQIAKWGQLGKNFQIITTYAQTELGHGTYLQGLETEATYDATTQEFVIHSPTMTSIKWWPGDL 195

  Fly   158 NVTLGLQTHRVVVDLLKEVGT------------PLQQQRYLQDLATGKL---IGTEAI------- 200
            ..|:   ||.||:..|..:|.            .|:....|..:..|.:   :|.|.|
Mouse   196 GRTV---THAVVLAHLICLGARHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGFENIDNGFLRL 257

  Fly   201 YEISPPEEDYFNTTAELFPEYGKWQLNGEKSFVICTPGERQLFLVLAQTQQPNVPGVLGRGTTIF 265
            ..:..|.|:..:..||:.|: |.:|..|       ||....|.:::.:.|      :|.:|   |
Mouse   258 NHVRVPRENMLSRFAEVLPD-GTYQRLG-------TPQSNYLGMLVTRVQ------LLYKG---F 305

  Fly   266 LVDSQQEGVRLGEKHATFGCRKAEIRR--------------------------------VHFEGV 298
            |...|        |..|...|.|.||.                                :||...
Mouse   306 LPTLQ--------KACTIAVRYAVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYALHFMTT 362

  Fly   299 KLGEDQVVGLPHDGNRYSEQLVRSSRLRGSLVGLSLAKKLLNE--LAQYT-VNTTQCG----VQL 356
            .|       |....:.||:.|.|...|...|..||...|.::.  .||.| :....||    .:|
Mouse   363 SL-------LQFFHSSYSDILKRDFSLLPELHALSTGMKAMSSDFCAQGTEICRRACGGHGYSKL 420

  Fly   357 QDLELTRIHMSRAMCSVYAMESMLYLTAGLLDEFRAQDVTLESAITKYFTLRQVYAIASQNLGVV 421
            ..|. |.:..:.|.|:.....::|||                 .:.::  |.:.|..|..:.|.:
Mouse   421 SGLP-TLVTQAIASCTYEGENTVLYL-----------------QVARF--LMKSYLQAQVSPGSI 465

  Fly   422 GPKSLLSGE---TTELGLRDAAQLCTQ---GESLDTLGMFIALTGLQHAGQAMNTGVRKSRNPLF 480
            ..|.|....   .|....|..||....   .|...|...:::...::.|.|...|.:|
Mouse   466 PQKPLPQSVMYLATPRPARCPAQTAADFRCPEVYTTAWAYVSARLIRDATQHTQTLMR------- 523

  Fly   481 NPGHIFGKFLDNNSIDNPKTKMQLSEHVHPSLEAA-AQCIELSVARLQMAVELMFTKHGNAVVER 544
                        :.:|......|.|. :|  |:|| |.|..|:|...:.|||.:         :.
Mouse   524 ------------SGVDQYDAWNQTSV-IH--LQAAKAHCYFLTVRNFKEAVEKL---------DN 564

  Fly   545 QSEMQRLAEVGTLIYAM-----------------WASVARASRSYCIGLPL-------------- 578
            :.|:||:.:....:||:                 .|.|..|..::...|||
Mouse   565 EPEIQRVLQNLCDLYALNGILTNSGDFLHDGFLSGAQVDMARTAFLDLLPLIRKDAILLTDAFDF 629

  Fly   579 ADHELLTATAICSEG 593
            :||.|.:|.. |.:|
Mouse   630 SDHCLNSALG-CYDG 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	86/430 (20%)
		CaiA	122..439	CDD:224871	80/405 (20%)
Acox2	NP_001155139.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		AXO	20..655	CDD:173839	120/599 (20%)
		Microbody targeting signal. /evidence=ECO:0000255	679..681

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900