Protein Alignment Egm and POX1

DIOPT Version :10

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_011310.1
• Gene: POX1 / 852667
• SGDID: S000003173
• Length: 748
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 130/695 - (18%)
• Similarity: 222/695 - (31%)
• Gaps: 268/695 - (38%)

  Fly    49 RAES----------VEESPEQQ-------------------------RKLPTREPLAKNFFIGVV 78
            ||:|          :|.|||::                         :|:..||..||..
Yeast    24 RADSKIKVDQVNTFLESSPERRTLTHALIDQIVNDPILKTDTDYYDAKKMQEREITAKKI----- 83

  Fly    79 DKELLAYPEVIPRDEMAQLENSLLPLKNYF--------VEPRETEETSPETLRQLGLYGLNVSTD 135
             ..|.:|           :|:.:..::.:|        ::..:.::.||.|.:.|.::...:
Yeast    84 -ARLASY-----------MEHDIKTVRKHFRDTDLMKELQANDPDKASPLTNKDLFIFDKRL--- 133

  Fly   136 YEGKGYGWSASLMAS-EPD-STDINVTLGL--------QTHRVVVDLLKEVGTPLQQQRY----L 186
                      ||:|: :|. .|.:.|.|||        .|...:...|:|.|..|.:..|    :
Yeast   134 ----------SLVANIDPQLGTRVGVHLGLFGNCIKGNGTDEQIRYWLQERGATLMKGIYGCFAM 188

  Fly   187 QDLATGKLIG---TEAIYEISPPEEDYF-----NTTAELFPEYGKWQLNGE-------------- 229
            .:|..|..:.   |.|:|:   .:.|.|     :.||.      ||.:.|.
Yeast   189 TELGHGSNVAQLQTRAVYD---KQNDTFVIDTPDLTAT------KWWIGGAAHSATHAAVYARLI 244

  Fly   230 --------KSFVICTP-GERQLFLVLAQTQQPNVPGVLGR------------------------- 260
                    |:||:  | .:...|.:||.....::...:||
Yeast   245 VEGKDYGVKTFVV--PLRDPSTFQLLAGVSIGDIGAKMGRDGIDNGWIQFRNVVIPREFMLSRFT 307

  Fly   261 ----------------------GTTIFL---VDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVK- 299
                                  |.:..|   |:...:..|.|.|.||...|.| :.|..|...|
Yeast   308 KVVRSPDGSVTVKTEPQLDQISGYSALLSGRVNMVMDSFRFGSKFATIAVRYA-VGRQQFAPRKG 371

  Fly   300 LGEDQVVGLPHDGNRYSEQL--------------------------VRSSRLRGSLVGLSLAKKL 338
            |.|.|::..|....|...||                          ..||..:.:||  :::|||
Yeast   372 LSETQLIDYPLHQYRVLPQLCVPYLVSPVAFKLMDNYYSTLDELYNASSSAYKAALV--TVSKKL 434

  Fly   339 LN----ELAQYTVNTTQCGVQLQDLELTRIHMSRA--------------MCSVYAMESMLYLTA- 384
            .|    ..:....||......:.:|..|......:              .|:.....::|.||:
Yeast   435 KNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCTWEGDNNVLSLTSA 499

  Fly   385 -GLLDEFRAQ------DVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTELG------- 435
             .:|.:|...      |.||:.....|...:.:.::.|..: ..|.|.|  |:.||:.
Yeast   500 KSILKKFIDSATKGRFDNTLDVDSFSYLKPQYIGSVVSGEI-KSGLKEL--GDYTEIWSITLIKL 561

  Fly   436 LRDAAQLCTQGESLDTLGMFIALTGLQHAGQAM-NTGVRK------------SRNPLFNPGHIFG 487
            |.....|..:..|:|::...:.|....||.:.| .|...|            ::..::|...:|.
Yeast   562 LAHIGTLVEKSRSIDSVSKLLVLVSKFHALRCMLKTYYDKLNSRDSHISDEITKESMWNVYKLFS 626

  Fly   488 -KFLDNNSIDNPKTKM----QLSEHVHPSLEA-----AAQCIELS 522
             .|:|.:|.:..:.|:    |:|:.|.|.|.|     ...||.|:
Yeast   627 LYFIDKHSGEFQQFKIFTPDQISKVVQPQLLALLPIVRKDCIGLT 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	95/527 (18%)
POX1	NP_011310.1	AXO	18..702	CDD:173839	130/695 (19%)