Protein Alignment Egm and Acox1

DIOPT Version :9

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_059036.1
• Gene: Acox1 / 50681
• RGDID: 619757
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 675
• Identity: 119/675 - (17%)
• Similarity: 215/675 - (31%)
• Gaps: 252/675 - (37%)

  Fly    53 VEESPEQQRKLPTREPLAKNFFIGVVDKELLAYPEVIPRDEMAQLENSLLPLKNYFVEPRETEET 117
            ::.|||..|:  .||          ::..:|..|:....|     .|.|...:.|.|..::
  Rat    23 LDGSPENTRR--RRE----------IENLILNDPDFQHED-----YNFLTRSQRYEVAVKK---- 66

  Fly   118 SPETLRQLGLYGLNVSTDYEGKGYGWSASLMAS---EPDSTDINVTLGLQTHRVVVDLLKEVGTP 179
            |...::::..||::     :.:...|...|..:   ||        :||.....:..||.: ||.
  Rat    67 SATMVKKMREYGIS-----DPEEIMWFKKLYLANFVEP--------VGLNYSMFIPTLLNQ-GTT 117

  Fly   180 LQQQRYLQDLATGKLIGTEAIYEISPPEEDYFNTTAELFPEYGKWQLNGEKSFVICTPGERQLFL 244
            .||:::::.....::|||.|..|:.                :|. .|.|.::.....|..::..|
  Rat   118 AQQEKWMRPSQELQIIGTYAQTEMG----------------HGT-HLRGLETTATYDPKTQEFIL 165

  Fly   245 VLAQTQQPNV------PGVLGR------------------GTTIFLVDSQQ-------EGVRLGE 278
                 ..|.|      ||.||:                  |...|:|..::       .|:.:|:
  Rat   166 -----NSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGD 225

  Fly   279 KHATFGCRKAEIRRVHFEGVKLGEDQVV----GLPHDGNRYSEQLVRSSRL--------RGSLVG 331
            ....||..:.:...:..:..::..:.::    .:..||. |.:.|  |::|        |..|||
  Rat   226 IGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGT-YVKPL--SNKLTYGTMVFVRSFLVG 287

  Fly   332 ---LSLAKKLLNEL------AQYTVNTTQCGVQLQDLELTRIHMSRAMCSVYAMESMLYLTAGLL 387
               .||:|.....:      .|..:..::...|:.|.:..:..:...:.:.||..
  Rat   288 NAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFH---------- 342

  Fly   388 DEFRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTEL--------GLRDAAQLCT 444
                        .:.:|  :::.|...::::|        .|:.:||        ||: |....|
  Rat   343 ------------FVGRY--MKETYLRINESIG--------QGDLSELPELHALTAGLK-AFTTWT 384

  Fly   445 QGESLDTLGMFIALTGLQHAGQAMNTGVRKSRNPLFNPGHIFGKFLDNNSIDNPKTKMQL----- 504
            ....::...|.....|..|:....|..|      .|.|...|         :...|.|.|
  Rat   385 ANAGIEECRMACGGHGYSHSSGIPNIYV------TFTPACTF---------EGENTVMMLQTARF 434

  Fly   505 -------------------------SEHVHP-------------SLEAAAQCIELSVARLQMAVE 531
                                     |:.:.|             |||...:..:|..|||   ||
  Rat   435 LMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARL---VE 496

  Fly   532 LMFTKHGNAVVERQSEMQRLAEVGTLIYAMW----ASVARASRSYC---------IGLPLADHEL 583
            :........|..|:|:     ||.      |    ..:.|||.::|         ..||....:.
  Rat   497 IAAKNLQTHVSHRKSK-----EVA------WNLTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKA 550

  Fly   584 LTATAICSEGRDRVRTLCT--EIYG 606
            :.|.         :|.||.  .:||
  Rat   551 VQAV---------LRNLCLLYSLYG 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	72/427 (17%)
		CaiA	122..439	CDD:224871	63/379 (17%)
Acox1	NP_059036.1	AXO	3..638	CDD:173839	119/675 (18%)
		Microbody targeting signal	659..661

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900