Protein Alignment Egm and ACADVL

DIOPT Version :9

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001257376.1
• Gene: ACADVL / 37
• HGNCID: 92
• Length: 678
• Species: Homo sapiens
• Alignment Length: 653
• Identity: 160/653 - (24%)
• Similarity: 278/653 - (42%)
• Gaps: 79/653 - (12%)

  Fly    25 GRSTKATSSSLDSQHQDAATTEGGRAESVEESPEQQRKLPTREPLAKNFFIGVVDKEL-----LA 84
            |.:.:......||...||.|                ||.|.:.. :|:|.:|:...:|     ..
Human    65 GGAAQLALDKSDSHPSDALT----------------RKKPAKAE-SKSFAVGMFKGQLTTDQVFP 112

  Fly    85 YPEVIPRDEMAQLENSLLPLKNYFVEPRE---------TEETSPETLRQLGLYGLNVSTDYEGKG 140
            ||.|:..::...|:..:.|:..:|.|..:         .|||:.:.|::||.:||.|.::..|.|
Human   113 YPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVG 177

  Fly   141 -----YGWSASLMASEPDSTDINVTLGLQTHRVVVDLLKEV---GTPLQQQRYLQDLATGKLIGT 197
                 |.....::...    |:.|.:.|..|:.:.  .|.:   ||..|:::||..||:|:.:..
Human   178 LCNTQYARLVEIVGMH----DLGVGITLGAHQSIG--FKGILLFGTKAQKEKYLPKLASGETVAA 236

  Fly   198 EAIYEISPPEEDYFNTTAELFPEYGK-WQLNGEKSFVICTPGERQLFLVLAQTQQPN-VPGVLGR 260
            ..:.|.|...:.....|:.:....|| :.|||.|.: |...|...:|.|.|:|...: ..|.:..
Human   237 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLW-ISNGGLADIFTVFAKTPVTDPATGAVKE 300

  Fly   261 GTTIFLVDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVKLGEDQVVGLPHDGNRYSEQLVRSSR- 324
            ..|.|:|:....|:..|......|.:.:....|.|:||::..:.|:|....|.:.:..::.:.|
Human   301 KITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRF 365

  Fly   325 -----LRGSLVGLSLAKKLLNELAQYTVNTTQCGVQLQDLELTRIHMSRAMCSVYAMESMLYLTA 384
                 |.|::.|: :||.:     .:..|.||.|.::.:..|.:..::|.:...|..|||.|:.:
Human   366 GMAAALAGTMRGI-IAKAV-----DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVS 424

  Fly   385 GLLDEFRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTELGLRDAAQLCTQGESL 449
            ..:|: .|.|..:|:||:|.|.....:.:..:.:.::|....:.....|..|||.........:.
Human   425 ANMDQ-GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTN 488

  Fly   450 DTLGMFIALTGLQHAGQAMNTGVRKSRNPLFNPGHIF---GKFLDNNSIDNPKTKMQLSEHVHPS 511
            |.|.:|:||.|....|:.::......:||..|.|.:.   ||.|...:  ...:.:.||..|||.
Human   489 DILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRA--GLGSGLSLSGLVHPE 551

  Fly   512 LEAAAQCIELSVARLQMAVELMFTKHGNAVVERQSEMQRLAEVGTLIYAMWASVARASRSYCIGL 576
            |..:.:....::.:....||....||...:|..|..:||||:....:|||...::|||||...|.
Human   552 LSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGH 616

  Fly   577 PLADHELLTATAICSEGRDRVRTLCTEIYGGHFVNND-------NNLVRLSKQVAKSKGYFAVHP 634
            |.|.||.:.....|.|...|:|.      |...:.:|       .|...:||.:.:..|....:|
Human   617 PTAQHEKMLCDTWCIEAAARIRE------GMAALQSDPWQQELYRNFKSISKALVERGGVVTSNP 675

  Fly   635 LTF 637
            |.|
Human   676 LGF 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	91/389 (23%)
		CaiA	122..439	CDD:224871	80/332 (24%)
ACADVL	NP_001257376.1	VLCAD	95..504	CDD:173850	100/422 (24%)
		CaiA	125..496	CDD:224871	91/384 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D163462at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820