Protein Alignment Egm and Gcdh

DIOPT Version :9

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001102366.1
• Gene: Gcdh / 364975
• RGDID: 1308829
• Length: 447
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 110/525 - (20%)
• Similarity: 189/525 - (36%)
• Gaps: 147/525 - (28%)

  Fly     1 MRPNLFSGASRLLTYSRNGKLLTR------GRSTKATSSSLDSQHQDAATTEGGRAESVEESPEQ 59
            |.|.:.:|...|...|  ..||:|      .|..:..||:       ||.||..:..||:.|
  Rat     1 MVPAMLTGYMSLRGVS--AWLLSRKLGLRFSRVPRTWSSA-------AAHTEKTQIRSVKSS--- 53

  Fly    60 QRKLPTREPLAKNFFIGVVDKELLAYPEVIPRDEMAQ------LENSLLPLKNYFVEPRETEETS 118
            :.....::||       |::::|.|..::| ||....      :...||..:|.........|
  Rat    54 RPVFDWKDPL-------VLEEQLTADEKLI-RDTFRNYCQERLMSRILLANRNEVFHRDIVYE-- 108

  Fly   119 PETLRQLGLYGLNVSTDYEGKGYGWSA------SLMASEPDSTD------INVTLGLQTHRVVVD 171
               :.:||:.|..:      ||||.:.      .|:..|.:..|      ::|...|..|.:..
  Rat   109 ---MGELGVLGPTI------KGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYT- 163

  Fly   172 LLKEVGTPLQQQRYLQDLATGKLIG----TEAIYEISPPEEDYFNTTAELFPEYGKWQLNGEKSF 232
                .|:..|:|:||..||.|:|:|    ||..:...|..   ..|.|...|....:.|:|.|::
  Rat   164 ----YGSEEQRQKYLPRLAKGELLGCFGLTEPNHGSDPGS---METRARHNPSNKSYTLSGTKTW 221

  Fly   233 VICTPGERQLFLVLAQTQQPNVPGVLGRGTTIFLVDSQQEGVRLGEKHATFGCRKAEIRRVHFEG 297
            :..:| ...||:|.|:.:...:.|        ||::....|:........|..|.:....:..:.
  Rat   222 ITNSP-VADLFVVWARCEDNCIRG--------FLLEKGMRGLSAPRIEGKFSLRASATGMIIMDS 277

  Fly   298 VKLGEDQVVGLPHDGNRYSEQLVRSSRLRGSLVG----------------LSLAKKLLNELAQYT 346
            |::.|:.|  ||:               ..||.|                |..|:..|:...||.
  Rat   278 VEVPEENV--LPN---------------VSSLAGPFGCLNTARYGITWGVLGAAEFCLHTARQYA 325

  Fly   347 VNTTQCGVQLQDLELTRIHMSRAMCSVYAMESMLYLTAGL-----LDEFRAQDVTLESAIT--KY 404
            ::..|.||.|...:|.:..::         :.:..:|.||     |...:.||......::  |.
  Rat   326 LDRIQFGVPLARNQLVQKKLA---------DMLTEITLGLHACLQLGRLKDQDKATPEMVSLLKR 381

  Fly   405 FTLRQVYAIASQNLGVVGPKSLLSGETTELGLRDAAQLCTQGESLDTLGMF------------IA 457
            ....:...||.|      .:.:|.|.    |:.|...:.....:|:.:..:            .|
  Rat   382 NNCGKALDIARQ------ARDILGGN----GISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRA 436

  Fly   458 LTGLQ 462
            :||:|
  Rat   437 ITGIQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	81/421 (19%)
		CaiA	122..439	CDD:224871	74/355 (21%)
Gcdh	NP_001102366.1	GCD	57..443	CDD:173840	92/457 (20%)
		CaiA	69..443	CDD:224871	89/438 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900