DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Egm and CG17544

DIOPT Version :9

Sequence 1:NP_610687.1 Gene:Egm / 36242 FlyBaseID:FBgn0086712 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001163015.1 Gene:CG17544 / 35213 FlyBaseID:FBgn0032775 Length:693 Species:Drosophila melanogaster


Alignment Length:576 Identity:112/576 - (19%)
Similarity:188/576 - (32%) Gaps:213/576 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 LLAYP-EVIPRDEMAQL-ENSLLPLKNYFVEPRETEETSPETLRQLGLYGLNVSTDYEGKGYGWS 144
            |.|:| ..:|.||..:| ...:..:|:..:.|:|.|..|           .:..|.|    ..:.
  Fly    57 LFAHPSRTLPMDEQKRLCAMQVNRMKHLDLVPKEIESLS-----------FSAKTKY----LMYI 106

  Fly   145 ASLMASEPDSTDINVTLGLQTHRVVVDLLKEVGTPLQQQRYLQDLATGKLIGTEAIYEIS-PPEE 208
            ...:|....|..:.:.||:....   :.::.:||. :.|:|::.....::|...||.|:| ....
  Fly   107 NEALACYSPSLSVKIALGVGLFN---NAIRAMGTE-KHQKYIEAAWNREVITCLAITELSHGSNT 167

  Fly   209 DYFNTTAELFPEYGKWQLNGEKSFVICTPG-ERQLFLVLAQTQQPNVPGVLGRGTTI-------F 265
            ....|||...|.        .:.|||.||. |.....|          |.||:..|:       :
  Fly   168 KSIRTTATYDPT--------TQEFVINTPDFEAAKCWV----------GNLGKTATVAMTFANLY 214

  Fly   266 LVDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVKLGEDQVVGLPHDGNRYSEQLVRSSRLRGSLV 330
            ..|.|..|                                                   |.|.|:
  Fly   215 TADGQNHG---------------------------------------------------LHGFLI 228

  Fly   331 GLSLAKKLLN-------ELAQYTVNTTQCGVQLQD---LELTRIHMSRAMCSVYAMESMLYLTAG 385
            .:...|.||:       ::.:      :||:...|   :..|...:.|               ..
  Fly   229 PIRDPKTLLSYPGVLVGDIGE------KCGLNGIDNGFVVFTNYRIPR---------------DN 272

  Fly   386 LLDEFRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTELGLRDAAQLCTQGESLD 450
            ||:  |..|||.|......||          ..|.|...:|.|.....:|:..        ||.:
  Fly   273 LLN--RTSDVTPEGVYESVFT----------EPGKVLGAALESFSAGRIGIMQ--------ESAN 317

  Fly   451 TLGMFIALTGLQHAGQAMNTGVRKSRNPLFNPGHIFGKFLDNNSIDNPKTKMQLSEH-VHPSLEA 514
            || ...|:..:::      :.|||...|            :.:..:....:.||.:: :.|.|  
  Fly   318 TL-CSAAVIAVRY------SAVRKQFGP------------ERHGEEMAILEYQLHQYRIFPYL-- 361

  Fly   515 AAQCIELSVARLQMAVELMFTKHGNAVVERQSE-------MQRLAEVGTLIYA-----MWAS--V 565
            ||.|::      ::|.|.:.:.:...:...|::       .|..||:..||.:     .||:  .
  Fly   362 AAACVQ------KIATEELTSTYMEIIARSQADSNGFDVLTQNAAEIHALISSSKPLITWAARDA 420

  Fly   566 ARASRSYCIGLPLADHELLTATAICSEGRDRVRT----LCTEIYGGHFVNNDNNLV 617
            .:.:|..|.|     |..|.|..:     .::||    |||  |.|     |||::
  Fly   421 IQEAREACGG-----HGYLQAAKL-----GQMRTDHDPLCT--YEG-----DNNVL 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EgmNP_610687.1 ACAD 92..457 CDD:173838 70/384 (18%)
CaiA 122..439 CDD:224871 58/335 (17%)
CG17544NP_001163015.1 AXO 16..670 CDD:173839 112/576 (19%)
PLN02443 18..687 CDD:178062 112/576 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1960
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.