Protein Alignment Egm and Gcdh

DIOPT Version :9

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001038209.2
• Gene: Gcdh / 270076
• MGIID: 104541
• Length: 447
• Species: Mus musculus
• Alignment Length: 526
• Identity: 106/526 - (20%)
• Similarity: 190/526 - (36%)
• Gaps: 149/526 - (28%)

  Fly     1 MRPNLFSG-------ASRLLTYSRNGKLLTRGRSTKATSSSLDSQHQDAATTEGGRAESVEESPE 58
            |.|.:.:|       ::|||: .|:|  |...|..:..||:       ||.||   ...:..:..
Mouse     1 MVPAMLTGYMSLRGVSARLLS-RRSG--LRFPRFPRTWSSA-------AAHTE---KTQIRPAKS 52

  Fly    59 QQRKLPTREPLAKNFFIGVVDKELLAYPEVIPRDEMAQ------LENSLLPLKNYFVEPRETEET 117
            .:.....::||       :::::|.|..::| ||....      :...||..:|.........|
Mouse    53 SRPVFDWKDPL-------ILEEQLTADEKLI-RDTFRNYCQERLMSRILLANRNEVFHRDIVYE- 108

  Fly   118 SPETLRQLGLYGLNVSTDYEGKGYGWSA------SLMASEPDSTD------INVTLGLQTHRVVV 170
                :.:||:.|..:      ||||.:.      .|:..|.:..|      ::|...|..|.:..
Mouse   109 ----MGELGVLGPTI------KGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYT 163

  Fly   171 DLLKEVGTPLQQQRYLQDLATGKLIG----TEAIYEISPPEEDYFNTTAELFPEYGKWQLNGEKS 231
                 .|:..|:|:||..||.|:|:|    ||..:...|   ....|.|...|....:.|:|.|:
Mouse   164 -----YGSEEQRQKYLPGLAKGELLGCFGLTEPNHGSDP---GGMETRARHNPSNQSYTLSGTKT 220

  Fly   232 FVICTPGERQLFLVLAQTQQPNVPGVLGRGTTIFLVDSQQEGVRLGEKHATFGCRKAEIRRVHFE 296
            ::..:| ...||:|.|:.:...:.|        |:::....|:........|..|.:....:..:
Mouse   221 WITNSP-VADLFIVWARCEDNCIRG--------FILEKGMRGLSAPRIEGKFSLRASATGMIIMD 276

  Fly   297 GVKLGEDQVVGLPHDGNRYSEQLVRSSRLRGSLVG----------------LSLAKKLLNELAQY 345
            .|::.|:.|  ||:               ..||.|                |..|:..|:...||
Mouse   277 SVEVPEENV--LPN---------------VSSLAGPFGCLNTARYGITWGVLGAAEFCLHTARQY 324

  Fly   346 TVNTTQCGVQLQDLELTRIHMSRAMCSVYAMESMLYLTAGL-----LDEFRAQDVTLESAIT--K 403
            .::..|.||.|...:|.:..::         :.:..:|.||     |...:.||......::  |
Mouse   325 ALDRIQFGVPLARNQLVQKKLA---------DMLTEITLGLHACLQLGRLKDQDKATPEMVSMLK 380

  Fly   404 YFTLRQVYAIASQNLGVVGPKSLLSGETTELGLRDAAQLCTQGESLDTLGMF------------I 456
            .....:...||.|      .:.:|.|.    |:.|...:.....:|:.:..:            .
Mouse   381 RNNCGKALDIARQ------ARDILGGN----GISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 435

  Fly   457 ALTGLQ 462
            |:||:|
Mouse   436 AITGIQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	80/421 (19%)
		CaiA	122..439	CDD:224871	73/355 (21%)
Gcdh	NP_001038209.2	GCD	57..443	CDD:173840	90/457 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900