Protein Alignment Egm and acdh-13

DIOPT Version :9

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_501452.1
• Gene: acdh-13 / 177654
• WormBaseID: WBGene00001566
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 607
• Identity: 147/607 - (24%)
• Similarity: 261/607 - (42%)
• Gaps: 72/607 - (11%)

  Fly    66 REPLAKNFFIGVVDKELLAYPEVIPRDEMAQLENSL--------LPLKNYFVEPRETEETSP--E 120
            :..|::.|.:...:|:.:.|||....|::..:|..:        |.:.:..:| :|.:..|.  |
 Worm    50 KRSLSRGFAMNKFEKDFMIYPEYTDSDDVRNIEGFVDVLRKSLELSVDSKLIE-KEGKLASDTIE 113

  Fly   121 TLRQLGLYGLNVSTDYEGKGYGWSASLMASEPDSTDINVTLGLQTHRVVVDLLKEVGTPLQQQRY 185
            .||...::.|.:...::|.|..........|..|.|.||........:|.::|...|:..|:.:|
 Worm   114 ALRSNAIFSLAIGKYFDGIGMCNKDLSKVFEELSVDWNVYTTSHISLLVANILTIYGSDEQKSKY 178

  Fly   186 LQDLATGKLIGTEAIYEISPPEEDYFNTTAELFPEY----GKWQLNGEKSFVICTPGERQLFLVL 246
            |..|.:|||....||.:         :|...:..:.    ||..|||:...|:   |.
 Worm   179 LGILGSGKLRPAVAIVK---------DTNGGVCEQTAGPGGKSMLNGQNIRVM---GH------- 224

  Fly   247 AQTQQPNVPGVLGRGT---TIFLVDSQQEGVR---LGEKHATFGCRKAEIRRVHFEGVKLGEDQV 305
               ...|...|.|...   |.||:|..:.|..   ...:..|.|.:..::.|:....: :.:..:
 Worm   225 ---HNANFYVVFGNNNGEKTCFLLDEAELGTTDKIQFTRDETIGLKGIDVGRIELTAL-VTDKNL 285

  Fly   306 VGLPHDGNRYSEQLVRSSRLRGSLVGLSLAKKLLNELAQY---TVNTTQCGVQLQDLELTRIHMS 367
            :|.|..|:..:.:||.|.|:..:...:.:|::.|.||:.:   |.:.......|.|...::..::
 Worm   286 LGTPGHGSEIASELVGSGRMPFAAATIGMARRALRELSIWCNRTPSRQNDRTTLADDSRSQRIVT 350

  Fly   368 RAMCSVYAMESMLYLTAGLLDEFRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETT 432
            .....|||:||.||..:||:||..:..|.:|:::....|...:.|:.|..|.:||..:..:....
 Worm   351 ELALKVYALESSLYYLSGLIDEGLSVVVDIENSLLSIMTRDVLQAVISAQLELVGVAASDASFPH 415

  Fly   433 ELGLRDAAQLCT---QGESLDTLGMFIALTGLQHAGQAMNTGVRKSRNPLFNPGHIFGKFLDN-- 492
            |...||...|.:   :|..::.:|:....|      .|.:|..::..:.|       .::|.|
 Worm   416 EKLFRDVTTLLSIIDEGADVEQIGLATIAT------WATSTSHKRVVSTL-------KRWLKNEK 467

  Fly   493 --NSIDNPKTKMQLSEHVHPSLEAAAQCIELSVARLQMAVELMFTKHGNAVVERQSEMQRLAEVG 555
              :.:.||.....::||.||||:.|.|.:|.|::|:...|..:.|..|..:.:....::.|..|.
 Worm   468 EADELRNPGLSHYIAEHAHPSLQLACQELEFSMSRINNVVSKLLTSQGKNIEQDYGSLEALVNVL 532

  Fly   556 TLIYAMWASVARASRSYCIGLPLADHELLTATAICSE-GRDRVRTL--CTEIYGGHFVNNDNNLV 617
            .....|.::::||||||.|||..||.||..||.|||. .|.....|  .::::|  .|..:.:|:
 Worm   533 KNNLVMVSTISRASRSYSIGLRNADIELAWATIICSRLSRATWFELDSLSDLFG--LVRFNPSLL 595

  Fly   618 RLSKQVAKSKGYFAVHPLTFNF 639
            ...:.|....||....||..|:
 Worm   596 NAGRAVFDLGGYIIESPLEKNW 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	87/390 (22%)
		CaiA	122..439	CDD:224871	76/329 (23%)
acdh-13	NP_501452.1	ACAD	57..434	CDD:299127	91/400 (23%)
		CaiA	102..437	CDD:224871	83/358 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910