DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tou and GCN5

DIOPT Version :9

Sequence 1:	NP_001097270.1	Gene:	tou / 36241	FlyBaseID:	FBgn0033636	Length:	3131	Species:	Drosophila melanogaster
Sequence 2:	NP_011768.1	Gene:	GCN5 / 853167	SGDID:	S000003484	Length:	439	Species:	Saccharomyces cerevisiae

Alignment Length:	144	Identity:	49/144 - (34%)
Similarity:	78/144 - (54%)	Gaps:	15/144 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  2992 NQMSP-PPINIHAIQEA-----KEKLKQE-KKEKHATKKLMKELAVCKTLLGEMELHEDSWPFLL 3049
            |.:.| .|:.|..::||     .:.|.|. |:..|.        |..:.:|.|::.|..:||||.
Yeast   298 NNIKPIDPMTIPGLKEAGWTPEMDALAQRPKRGPHD--------AAIQNILTELQNHAAAWPFLQ 354

  Fly  3050 PVNTKQFPTYRKIIKTPMDLSTIKKKLQDLSYKTREDFCVDVRQIFDNCEMFNEDDSPVGKAGHG 3114
            |||.::.|.|...||.||||||::.||:...|:..|||..|.|.:|:||.|:|.:::...|..:.
Yeast   355 PVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANR 419

  Fly  3115 MRKFFESRWGELTD 3128
            :.|||.::..|:.:
Yeast   420 LEKFFNNKVKEIPE 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tou	NP_001097270.1	HAT_MBD	953..1027	CDD:238691
		ZapA	1021..1127	CDD:294720
		MAP7	1043..1198	CDD:283355
		RILP-like	1085..>1179	CDD:304877
		DDT	1255..1317	CDD:280886
		WHIM1	1406..1455	CDD:292246
		WHIM3	2190..2224	CDD:292248
		PHD_BAZ2A_like	2640..2685	CDD:277020
		RanBP2-type Zn finger	2640..2659	CDD:275375
		RanBP2-type Zn finger	2680..2698	CDD:275376
		PHD	2695..2744	CDD:279022
		Bromo_BAZ2A_B_like	3027..3123	CDD:99935	38/95 (40%)
GCN5	NP_011768.1	COG5076	77..439	CDD:227408	49/144 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900