DRSC/TRiP Functional Genomics Resources

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Protein Alignment tou and Brd4

DIOPT Version :9

Sequence 1:NP_001097270.1 Gene:tou / 36241 FlyBaseID:FBgn0033636 Length:3131 Species:Drosophila melanogaster
Sequence 2:NP_001273559.1 Gene:Brd4 / 57261 MGIID:1888520 Length:1401 Species:Mus musculus


Alignment Length:274 Identity:76/274 - (27%)
Similarity:117/274 - (42%) Gaps:51/274 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly  2877 PGGANVMPGVYPVYTPVAAGNFSAGLINQAPVQPAMPFANVVAMSPRAVTPTRTRTPTPTPAPTP 2941
            |..|...|  :|..||        .||.|.||...:|             |...:||:|.|...|
Mouse   219 PVQATTHP--FPAVTP--------DLIAQPPVMTMVP-------------PQPLQTPSPVPPQPP 260

  Fly  2942 PPPPPTPLLMQASPTATALHVNACQSPPQQQHAQLMTMPS-------PPAIGVGTATNQMSPPPI 2999
            |||.|.|..:|:.|...|......::....:.....|.|:       ||::.....|.::.|.  
Mouse   261 PPPAPVPQPVQSHPPIIATTPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLAPEPKTAKLGPR-- 323

  Fly  3000 NIHAIQEAKEKLKQEKK-----EKH----ATKKLMKELAVCKTLLGEMELHED---SWPFLLPVN 3052
                 :|:...:|..||     ::|    .:.|:.::|..|..:|.||...:.   :|||..||:
Mouse   324 -----RESSRPVKPPKKDVPDSQQHPGPEKSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVD 383

  Fly  3053 TKQ--FPTYRKIIKTPMDLSTIKKKLQDLSYKTREDFCVDVRQIFDNCEMFNEDDSPVGKAGHGM 3115
            .:.  ...|..|||.|||:||||.||:...|:..::|..|||.:|.||..:|..|..|......:
Mouse   384 VEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKL 448

  Fly  3116 RKFFESRWGELTDK 3129
            :..||.|:.::.|:
Mouse   449 QDVFEMRFAKMPDE 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
touNP_001097270.1 HAT_MBD 953..1027 CDD:238691
ZapA 1021..1127 CDD:294720
MAP7 1043..1198 CDD:283355
RILP-like 1085..>1179 CDD:304877
DDT 1255..1317 CDD:280886
WHIM1 1406..1455 CDD:292246
WHIM3 2190..2224 CDD:292248
PHD_BAZ2A_like 2640..2685 CDD:277020
RanBP2-type Zn finger 2640..2659 CDD:275375
RanBP2-type Zn finger 2680..2698 CDD:275376
PHD 2695..2744 CDD:279022
Bromo_BAZ2A_B_like 3027..3123 CDD:99935 36/100 (36%)
Brd4NP_001273559.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..58
Bromo_Brdt_I_like 58..164 CDD:99929
Bromo_Brdt_II_like 355..456 CDD:99930 36/100 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 462..617 0/1 (0%)
NPS region. /evidence=ECO:0000250 486..505
BID region. /evidence=ECO:0000250 526..581
BET 611..675 CDD:407211
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 676..1126
PHA03247 <793..1231 CDD:223021
C-terminal (CTD) region. /evidence=ECO:0000250 1051..1401
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1156..1378
TPH <1267..1308 CDD:404709
BRD4_CDT 1359..1401 CDD:407248
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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