DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tou and Chd5

DIOPT Version :9

Sequence 1:NP_001097270.1 Gene:tou / 36241 FlyBaseID:FBgn0033636 Length:3131 Species:Drosophila melanogaster
Sequence 2:XP_006538992.1 Gene:Chd5 / 269610 MGIID:3036258 Length:1955 Species:Mus musculus


Alignment Length:432 Identity:86/432 - (19%)
Similarity:137/432 - (31%) Gaps:200/432 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly  2502 KSIMKAYATKNKSSKKKSSAKKQA-----------------TPSKKQQQK-KNKKEQQLTPNGKE 2548
            |.:.::.::|.|..||:.|..:.:                 :|:||:::| |.|||:      ||
Mouse    53 KKLKESKSSKGKRKKKEGSNDEMSDNEEDLEEKSESEGSDYSPTKKKKKKLKEKKEK------KE 111

  Fly  2549 SKSK-------------SAINKPENQAPLSIK------------------INLKALAQNGQCLLK 2582
            .|.|             ..:.:|::...|..:                  .|.||.:|..:.|:.
Mouse   112 KKEKRKKRGEDEDDNDDGGLKEPKSSGQLMAEWGLDDVDYLFSEDDYHTLTNYKAFSQFLRPLIA 176

  Fly  2583 TKTP----------------------------------------------PILTKSPTASPSSHP 2601
            .|.|                                              |.|..||...|.:.|
Mouse   177 KKNPKIPMSKMMTVLGAKWREFSANNPFKGSSAAAAAAAVAAAVETVTIAPPLAISPQQVPQTLP 241

  Fly  2602 -----------------NTSDSDSD--------------FGKRTKKKSGGK----RRRSANNTNS 2631
                             |....||.              ||..:|:|.|..    .|..::..|:
Mouse   242 IRKAKTKEGKGPGVRKKNKGAKDSKKKGRGKRVAGLKFRFGGISKRKKGSSSEEDEREDSDLDNA 306

  Fly  2632 SKYSNSLQN--------------------------------CQFCTSGENEDKLLLCDGCDKGYH 2664
            |.:|:|:::                                |:.|..|   .:::|||.|.:.||
Mouse   307 SIHSSSVRSECSAALGKKNKRRRKKKRIDDGDGYETDHQDYCEVCQQG---GEIILCDTCPRAYH 368

  Fly  2665 TYCFKPKMDNIPDGDWYCYECVN-------KATNERK---------------CIVCGGHRPSPVG 2707
            ..|..|:::..|:|.|.|..|..       |..:|.:               |.||     ...|
Mouse   369 LVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDEEEEEGGCEEEEDDHMEFCRVC-----KDGG 428

  Fly  2708 KMIYCDLCPRAYHADCYIPPLLKVPRGKWYCHGCISRAPPPK 2749
            :::.||.||.:||..|..|||.::|.|:|.|..|  ..||.|
Mouse   429 ELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC--TCPPLK 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
touNP_001097270.1 HAT_MBD 953..1027 CDD:238691
ZapA 1021..1127 CDD:294720
MAP7 1043..1198 CDD:283355
RILP-like 1085..>1179 CDD:304877
DDT 1255..1317 CDD:280886
WHIM1 1406..1455 CDD:292246
WHIM3 2190..2224 CDD:292248
PHD_BAZ2A_like 2640..2685 CDD:277020 15/76 (20%)
RanBP2-type Zn finger 2640..2659 CDD:275375 6/50 (12%)
RanBP2-type Zn finger 2680..2698 CDD:275376 6/39 (15%)
PHD 2695..2744 CDD:279022 19/48 (40%)
Bromo_BAZ2A_B_like 3027..3123 CDD:99935
Chd5XP_006538992.1 CHDNT 148..203 CDD:369683 7/54 (13%)
PHD1_CHD_II 347..389 CDD:277006 15/44 (34%)
PHD2_CHD_II 420..462 CDD:277007 18/46 (39%)
CD1_tandem_CHD3-4_like 467..546 CDD:349314 1/2 (50%)
CD2_tandem_CHD3-4_like 591..644 CDD:349309
PLN03142 700..>1218 CDD:215601
DUF1087 1300..1359 CDD:368924
DUF1086 1393..1534 CDD:368921
PRK13108 <1535..1687 CDD:237284
CHDCT2 1733..1904 CDD:369684
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0383
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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